靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

INTEPATH

faspathway:FAS (CD95) signaling pathway

INTEPATH

fgf_pathway:FGF signaling pathway

INTEPATH

il12_2pathway:IL12-mediated signaling events

INTEPATH

il2_1pathway:IL2-mediated signaling events

INTEPATH

il4_2pathway:IL4-mediated signaling events

INTEPATH

il6_7pathway:IL6-mediated signaling events

INTEPATH

lymphangiogenesis_pathway:VEGFR3 signaling in lymphatic endothelium

INTEPATH

mapktrkpathway:Trk receptor signaling mediated by the MAPK pathway

INTEPATH

nfat_3pathway:Role of Calcineurin-dependent NFAT signaling in lymphocytes

INTEPATH

nfkappabatypicalpathway:Atypical NF-kappaB pathway

INTEPATH

p38_mk2pathway:p38 signaling mediated by MAPKAP kinases

INTEPATH

p38_mkk3_6pathway:p38 MAPK signaling pathway

INTEPATH

p38alphabetadownstreampathway:Signaling mediated by p38-alpha and p38-beta

INTEPATH

p38alphabetapathway:Regulation of p38-alpha and p38-beta

INTEPATH

p53regulationpathway:p53 pathway

INTEPATH

p73pathway:p73 transcription factor network

INTEPATH

rac1_pathway:RAC1 signaling pathway

INTEPATH

rapid_gr_pathway:Rapid glucocorticoid signaling

INTEPATH

rb_1pathway:Regulation of retinoblastoma protein

INTEPATH

reg_gr_pathway:Glucocorticoid receptor regulatory network

目标的 KEGG 通路数据

标题	内容
hsa04010	MAPK signaling pathway
hsa04015	Rap1 signaling pathway
hsa04068	FoxO signaling pathway
hsa04071	Sphingolipid signaling pathway
hsa04261	Adrenergic signaling in cardiomyocytes
hsa04370	VEGF signaling pathway
hsa04380	Osteoclast differentiation
hsa04550	Signaling pathways regulating pluripotency of stem cells
hsa04611	Platelet activation
hsa04620	Toll-like receptor signaling pathway
hsa04621	NOD-like receptor signaling pathway
hsa04622	RIG-I-like receptor signaling pathway
hsa04660	T cell receptor signaling pathway
hsa04664	Fc epsilon RI signaling pathway
hsa04668	TNF signaling pathway
hsa04670	Leukocyte transendothelial migration
hsa04722	Neurotrophin signaling pathway
hsa04723	Retrograde endocannabinoid signaling
hsa04728	Dopaminergic synapse
hsa04750	Inflammatory mediator regulation of TRP channels
hsa04912	GnRH signaling pathway
hsa04914	Progesterone-mediated oocyte maturation
hsa04917	Prolactin signaling pathway
hsa05014	Amyotrophic lateral sclerosis (ALS)
hsa05120	Epithelial cell signaling in Helicobacter pylori infection
hsa05131	Shigellosis
hsa05132	Salmonella infection
hsa05133	Pertussis
hsa05140	Leishmaniasis
hsa05142	Chagas disease (American trypanosomiasis)
hsa05145	Toxoplasmosis
hsa05152	Tuberculosis
hsa05160	Hepatitis C
hsa05164	Influenza A
hsa05169	Epstein-Barr virus infection
hsa05205	Proteoglycans in cancer

目标的 Wiki 路径数据

标题	内容
WP75	Toll-like receptor signaling pathway
WP727	Monoamine Transport
WP722	Serotonin HTR1 Group and FOS Pathway
WP69	TCR Signaling Pathway
WP615	Senescence and Autophagy in Cancer
WP585	Interferon type I signaling pathways
WP481	Insulin Signaling
WP437	EGF/EGFR Signaling Pathway
WP422	MAPK Cascade
WP408	Oxidative Stress
WP400	p38 MAPK Signaling Pathway
WP395	IL-4 Signaling Pathway
WP382	MAPK Signaling Pathway
WP366	TGF beta Signaling Pathway
WP304	Kit receptor signaling pathway
WP2795	Cardiac Hypertrophic Response
WP2792	MAP kinase activation in TLR cascade
WP2733	Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
WP2643	Nanoparticle-mediated activation of receptor signaling
WP2637	Structural Pathway of Interleukin 1 (IL-1)
WP2593	JAK/STAT
WP2447	Amyotrophic lateral sclerosis (ALS)
WP244	Alpha 6 Beta 4 signaling pathway
WP2406	Cardiac Progenitor Differentiation
WP2380	BDNF signaling pathway
WP2377	Integrated Pancreatic Cancer Pathway
WP2374	Oncostatin M Signaling Pathway
WP2371	Parkinsons Disease Pathway
WP2355	Corticotropin-releasing hormone
WP2324	AGE/RAGE pathway
WP23	B Cell Receptor Signaling Pathway
WP2263	Prostate Cancer
WP2203	TSLP Signaling Pathway
WP2036	TWEAK Signaling Pathway
WP2035	FSH signaling pathway
WP2034	Leptin signaling pathway
WP2018	RANKL/RANK Signaling Pathway
WP2005	miR-targeted genes in muscle cell - TarBase
WP2004	miR-targeted genes in lymphocytes - TarBase
WP2003	miR-targeted genes in leukocytes - TarBase
WP2002	miR-targeted genes in epithelium - TarBase
WP195	IL-1 signaling pathway
WP1908	Signal amplification
WP1885	Platelet homeostasis
WP1873	NGF signalling via TRKA from the plasma membrane
WP1865	Myogenesis
WP1808	DSCAM interactions
WP1544	MicroRNAs in cardiomyocyte hypertrophy
WP1539	Angiogenesis
WP1528	Physiological and Pathological Hypertrophy of the Heart
WP1449	Regulation of toll-like receptor signaling pathway

目标的蛋白质ID

标题	内容
TARGETID	T65864
UNIPROID	MK14_HUMAN
TARGNAME	Stress-activated protein kinase 2a (p38 alpha)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
Stress-activated protein kinase 2a (p38 alpha)	MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES

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