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靶点信息25(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
L-selectin (SELL)
TARGTYPE
Clinical trial target
SYNONYMS
TQ1; SELL; Lymph node homing receptor; Leukocyte-endothelial cell adhesion molecule 1; Leukocyte surface antigen Leu-8; Leukocyte adhesion molecule-1; LECAM1; LAM-1; Gp90-MEL; CD62L
FUNCTION
Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.
PDBSTRUC
5VC1; 3CFW; 2LGF; 1KJB
SEQUENCE
MIFPWKCQSTQRDLWNIFKLWGWTMLCCDFLAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTCNCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSGLAFIIWLARRLKKGKKSKRSMNDPY
DRUGINFO
2,3,4-trihydroxybenzoic acid
KEGGPATH
hsa04514:Cell adhesion molecules (CAMs)
WIKIPATH
WP1794:Cell surface interactions at the vascular wall
WIKIPATH
WP1829:Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
WIKIPATH
WP2806:Human Complement System
目标的 Wiki 路径数据
| 标题 | 内容 |
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| WP2806 |
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| WP1829 |
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| WP1794 |
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目标的蛋白质ID
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| UNIPROID |
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