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靶点信息38(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Ornithine decarboxylase (ODC1)
TARGTYPE
Successful target
FUNCTION
Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis. Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine.
PDBSTRUC
5BWA; 4ZGY; 2OO0; 2ON3; 1D7K
BIOCLASS
Carbon-carbon lyase
SEQUENCE
MNNFGNEEFDCHFLDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSKAIVKTLAATGTGFDCASKTEIQLVQSLGVPPERIIYANPCKQVSQIKYAANNGVQMMTFDSEVELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLRTSRLLLERAKELNIDVVGVSFHVGSGCTDPETFVQAISDARCVFDMGAEVGFSMYLLDIGGGFPGSEDVKLKFEEITGVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKIVLKEQTGSDDEDESSEQTFMYYVNDGVYGSFNCILYDHAHVKPLLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCDLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPTIYYVMSGPAWQLMQQFQNPDFPPEVEEQDASTLPVSCAWESGMKRHRAACASASINV
DRUGINFO
(2R,5R)-delta-methyl-alpha-acetylenic putrescine
DRUGINFO
1-Amino-3-(aminoxy)-2-propanol Dihydrochloride
DRUGINFO
3-(Aminooxy)propan-1-amine hydrochloride
DRUGINFO
3-methoxy-4-hydroxylonchocarpin
DRUGINFO
4-hydroxylonchocarpin
DRUGINFO
Alpha-monofluoromethyl-3,4-dehydroornithine
目标的蛋白质ID
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| UNIPROID |
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目标的序列数据
| 标题 | 内容 |
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| Ornithine decarboxylase (ODC1) |
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