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靶点信息46(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Thymidine phosphorylase (TYMP)
TARGTYPE
Successful target
SYNONYMS
TdRPase; TYMP; TP; Platelet-derived endothelial cell growth factor; PDECGF; PD-ECGF; Gliostatin
FUNCTION
Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
PDBSTRUC
2WK6; 2WK5; 2J0F; 1UOU
BIOCLASS
Pentosyltransferase
SEQUENCE
MAALMTPGTGAPPAPGDFSGEGSQGLPDPSPEPKQLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVDSLPLITASILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAAALTAMDKPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAALDDGSALGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADGTVELVRALPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLRVHRDGPALSGPQSRALQEALVLSDRAPFAAPSPFAELVLPPQQ
DRUGINFO
1-(cyclohexyl)methyl-5'-O-tritylinosine
DRUGINFO
1-(cyclopropyl)methyl-5'-O-tritylinosine
DRUGINFO
1-allyl-5'-O-tritylinosine
DRUGINFO
1-benzyl-5'-O-tritylinosine
DRUGINFO
1-propyl-5'-O-tritylinosine
DRUGINFO
2'-aminoimidazolylmethyluracils
DRUGINFO
5-benzyl-6-chloropyrimidine-2,4(1H,3H)-dione
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa00240 |
|
| hsa00983 |
|
| hsa01100 |
|
| hsa05219 |
|
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP2828 |
|
| WP1851 |
|
| WP1601 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Thymidine phosphorylase (TYMP) |
|