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靶点信息10(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Thyrotropin-releasing hormone (TRH)
TARGTYPE
Clinical trial target
SYNONYMS
Prothyroliberin; Pro-thyrotropin-releasing hormone; Pro-TRH
FUNCTION
As a component of the hypothalamic-pituitary-thyroid axis, it controls the secretion of thyroid-stimulating hormone (TSH) and is involved in thyroid hormone synthesis regulation. It also operates as modulator of hair growth. It promotes hair-shaft elongation, prolongs the hair cycle growth phase (anagen) and antagonizes its termination (catagen) by TGFB2. It stimulates proliferation and inhibits apoptosis of hair matrix keratinocytes.
SEQUENCE
MPGPWLLLALALTLNLTGVPGGRAQPEAAQQEAVTAAEHPGLDDFLRQVERLLFLRENIQRLQGDQGEHSASQIFQSDWLSKRQHPGKREEEEEEGVEEEEEEEGGAVGPHKRQHPGRREDEASWSVDVTQHKRQHPGRRSPWLAYAVPKRQHPGRRLADPKAQRSWEEEEEEEEREEDLMPEKRQHPGKRALGGPCGPQGAYGQAGLLLGLLDDLSRSQGAEEKRQHPGRRAAWVREPLEE
目标的蛋白质ID
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目标的序列数据
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| Thyrotropin-releasing hormone (TRH) |
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