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靶点信息15(本栏目收费,不能显示细节,电话13136136841)
靶点信息
UNIPROID
GCYA1_HUMAN; GCYB1_HUMAN
TARGNAME
Soluble guanylate cyclase (GCS)
GENENAME
GUCY1A1; GUCY1B1
TARGTYPE
Successful target
SYNONYMS
GUCY1; GUCS; GUC1; GCS
FUNCTION
Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction.
BIOCLASS
Phosphorus-oxygen lyase
SEQUENCE
MFCTKLKDLKITGECPFSLLAPGQVPNESSEEAAGSSESCKATVPICQDIPEKNIQESLPQRKTSRSRVYLHTLAESICKLIFPEFERLNVALQRTLAKHKIKESRKSLEREDFEKTIAEQAVAAGVPVEVIKESLGEEVFKICYEEDENILGVVGGTLKDFLNSFSTLLKQSSHCQEAGKRGRLEDASILCLDKEDDFLHVYYFFPKRTTSLILPGIIKAAAHVLYETEVEVSLMPPCFHNDCSEFVNQPYLLYSVHMKSTKPSLSPSKPQSSLVIPTSLFCKTFPFHFMFDKDMTILQFGNGIRRLMNRRDFQGKPNFEEYFEILTPKINQTFSGIMTMLNMQFVVRVRRWDNSVKKSSRVMDLKGQMIYIVESSAILFLGSPCVDRLEDFTGRGLYLSDIPIHNALRDVVLIGEQARAQDGLKKRLGKLKATLEQAHQALEEEKKKTVDLLCSIFPCEVAQQLWQGQVVQAKKFSNVTMLFSDIVGFTAICSQCSPLQVITMLNALYTRFDQQCGELDVYKVETIGDAYCVAGGLHKESDTHAVQIALMALKMMELSDEVMSPHGEPIKMRIGLHSGSVFAGVVGVKMPRYCLFGNNVTLANKFESCSVPRKINVSPTTYRLLKDCPGFVFTPRSREELPPNFPSEIPGICHFLDAYQQGTNSKPCFQKKDVEDGNANFLGKASGID
DRUGINFO
Sodium nitroprusside
DRUGINFO
(5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol
目标的蛋白质ID
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目标的序列数据
| 标题 | 内容 |
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| Soluble guanylate cyclase (GCS) |
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