靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

INTEPATH

igf1_pathway:IGF1 pathway

INTEPATH

il2_1pathway:IL2-mediated signaling events

INTEPATH

kitpathway:Signaling events mediated by Stem cell factor receptor (c-Kit)

INTEPATH

mapktrkpathway:Trk receptor signaling mediated by the MAPK pathway

INTEPATH

met_pathway:Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

INTEPATH

mtor_4pathway:mTOR signaling pathway

INTEPATH

p38_mk2pathway:p38 signaling mediated by MAPKAP kinases

INTEPATH

pdgfrbpathway:PDGFR-beta signaling pathway

INTEPATH

pi3kciaktpathway:Class I PI3K signaling events mediated by Akt

INTEPATH

rb_1pathway:Regulation of retinoblastoma protein

INTEPATH

shp2_pathway:SHP2 signaling

INTEPATH

tcrraspathway:Ras signaling in the CD4+ TCR pathway

INTEPATH

vegfr1_2_pathway:Signaling events mediated by VEGFR1 and VEGFR2

PANTPATH

P00005:Angiogenesis

PANTPATH

P00010:B cell activation

PANTPATH

P00018:EGF receptor signaling pathway

PANTPATH

P00019:Endothelin signaling pathway

PANTPATH

P00021:FGF signaling pathway

PANTPATH

P00031:Inflammation mediated by chemokine and cytokine signaling pathway

PANTPATH

P00032:Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade

目标的 KEGG 通路数据

标题	内容
hsa04010	MAPK signaling pathway
hsa04012	ErbB signaling pathway
hsa04014	Ras signaling pathway
hsa04015	Rap1 signaling pathway
hsa04022	cGMP-PKG signaling pathway
hsa04024	cAMP signaling pathway
hsa04062	Chemokine signaling pathway
hsa04068	FoxO signaling pathway
hsa04071	Sphingolipid signaling pathway
hsa04151	PI3K-Akt signaling pathway
hsa04270	Vascular smooth muscle contraction
hsa04370	VEGF signaling pathway
hsa04510	Focal adhesion
hsa04540	Gap junction
hsa04550	Signaling pathways regulating pluripotency of stem cells
hsa04650	Natural killer cell mediated cytotoxicity
hsa04660	T cell receptor signaling pathway
hsa04662	B cell receptor signaling pathway
hsa04664	Fc epsilon RI signaling pathway
hsa04666	Fc gamma R-mediated phagocytosis
hsa04720	Long-term potentiation
hsa04722	Neurotrophin signaling pathway
hsa04726	Serotonergic synapse
hsa04730	Long-term depression
hsa04810	Regulation of actin cytoskeleton
hsa04910	Insulin signaling pathway
hsa04912	GnRH signaling pathway
hsa04914	Progesterone-mediated oocyte maturation
hsa04915	Estrogen signaling pathway
hsa04916	Melanogenesis
hsa04917	Prolactin signaling pathway
hsa04919	Thyroid hormone signaling pathway
hsa04921	Oxytocin signaling pathway
hsa05034	Alcoholism
hsa05152	Tuberculosis
hsa05160	Hepatitis C
hsa05161	Hepatitis B
hsa05164	Influenza A
hsa05200	Pathways in cancer
hsa05205	Proteoglycans in cancer
hsa05206	MicroRNAs in cancer
hsa05210	Colorectal cancer
hsa05211	Renal cell carcinoma
hsa05212	Pancreatic cancer
hsa05213	Endometrial cancer
hsa05214	Glioma
hsa05215	Prostate cancer
hsa05218	Melanoma
hsa05219	Bladder cancer
hsa05220	Chronic myeloid leukemia
hsa05221	Acute myeloid leukemia
hsa05223	Non-small cell lung cancer
hsa05230	Central carbon metabolism in cancer
hsa05231	Choline metabolism in cancer

目标的 Wiki 路径数据

标题	内容
WP2034	Leptin signaling pathway
WP1895	Rap1 signalling
WP185	Integrin-mediated Cell Adhesion
WP1823	GP1b-IX-V activation signalling
WP1544	MicroRNAs in cardiomyocyte hypertrophy
WP127	IL-5 Signaling Pathway
WP732	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
WP69	TCR Signaling Pathway
WP615	Senescence and Autophagy in Cancer
WP581	EPO Receptor Signaling
WP51	Regulation of Actin Cytoskeleton
WP49	IL-2 Signaling Pathway
WP481	Insulin Signaling
WP437	EGF/EGFR Signaling Pathway
WP422	MAPK Cascade
WP382	MAPK Signaling Pathway
WP366	TGF beta Signaling Pathway
WP313	Signaling of Hepatocyte Growth Factor Receptor
WP304	Kit receptor signaling pathway
WP2870	Extracellular vesicle-mediated signaling in recipient cells
WP286	IL-3 Signaling Pathway
WP2795	Cardiac Hypertrophic Response
WP2754	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
WP2735	RAF/MAP kinase cascade
WP2670	Iron uptake and transport
WP2643	Nanoparticle-mediated activation of receptor signaling
WP2526	PDGF Pathway
WP2446	Retinoblastoma (RB) in Cancer
WP2380	BDNF signaling pathway
WP2377	Integrated Pancreatic Cancer Pathway
WP2374	Oncostatin M Signaling Pathway
WP2355	Corticotropin-releasing hormone
WP2332	Interleukin-11 Signaling Pathway
WP2324	AGE/RAGE pathway
WP231	TNF alpha Signaling Pathway
WP23	B Cell Receptor Signaling Pathway
WP2263	Prostate Cancer
WP2261	Signaling Pathways in Glioblastoma
WP2197	Endothelin Pathways
WP2036	TWEAK Signaling Pathway
WP2035	FSH signaling pathway

目标的蛋白质ID

标题	内容
TARGETID	T52316
UNIPROID	RAF1_HUMAN
TARGNAME	Raf messenger RNA (Raf mRNA)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
Raf messenger RNA (Raf mRNA)	MEHIQGAWKTISNGFGFKDAVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRVFLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNSTIGDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIEDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF

标题

内容

Raf messenger RNA (Raf mRNA)

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