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靶点信息17(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
TNF superfamily receptor 12A (TNFRSF12A)
TARGTYPE
Clinical trial target
SYNONYMS
TweakR; Tweak-receptor; Tumor necrosis factor receptor superfamily member 12A; Fibroblast growth factor-inducible immediate-early response protein 14; FN14; FGF-inducible 14; CD266
FUNCTION
Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins. Receptor for TNFSF12/TWEAK.
PDBSTRUC
2RPJ; 2KMZ; 2EQP
BIOCLASS
Cytokine receptor
SEQUENCE
MARGSLRRLLRLLVLGLWLALLRSVAGEQAPGTAPCSRGSSWSADLDKCMDCASCRARPHSDFCLGCAAAPPAPFRLLWPILGGALSLTFVLGLLSGFLVWRRCRRREKFTTPIEETGGEGCPAVALIQ
KEGGPATH
hsa04060:Cytokine-cytokine receptor interaction
WIKIPATH
WP2036:TWEAK Signaling Pathway
REACPATH
R-HSA-5668541:TNFR2 non-canonical NF-kB pathway
REACPATH
R-HSA-5676594:TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
NET_PATH
NetPath_7:TGF_beta_Receptor Signaling Pathway
目标的蛋白质ID
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目标的序列数据
| 标题 | 内容 |
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| TNF superfamily receptor 12A (TNFRSF12A) |
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