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靶点信息62(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
GABA(A) receptor alpha-5 (GABRA5)
TARGTYPE
Successful target
SYNONYMS
GABRA5; GABAA alpha 5; GABA-A alpha-5
FUNCTION
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
PDBSTRUC
6A96; 5OJM; 5O8F
BIOCLASS
Ligand-gated ion channel
SEQUENCE
MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK
DRUGINFO
(2E,4S)-4-ammoniopent-2-enoate
DRUGINFO
(4R)-4-ammoniopentanoate
DRUGINFO
(4S)-4-ammoniopentanoate
DRUGINFO
[18F]fluoroethylflumazenil
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04080 |
|
| hsa04723 |
|
| hsa04727 |
|
| hsa05032 |
|
| hsa05033 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| GABA(A) receptor alpha-5 (GABRA5) |
|