主动脉瘤,家族性腹部
基因病名称(英)
Aortic aneurysm, familial abdominal
交叉引用
100070,C0162871,C1853365,D017544
描述(英)
A common multifactorial disorder characterized by permanent dilation of the abdominal aorta, usually due to degenerative changes in the aortic wall. Histologically, AAA is characterized by signs of chronic inflammation, destructive remodeling of the extracellular matrix, and depletion of vascular smooth muscle cells.
描述
一种常见的多因素疾病,其特征是腹主动脉永久性扩张,通常是由于主动脉壁的退行性变化。组织学上,AAA 的特征是慢性炎症、细胞外基质的破坏性重塑和血管平滑肌细胞的耗竭。