描述
Hypercholesterolemia literally means high blood cholesterol. The elevated cholesterol in the blood is due to abnormalities in the levels of lipoproteins, the LDL particles that carry cholesterol in the bloodstream. This disease can usually be attributed to one’s diet, genetic factors (such as LDL receptor mutations), and the presence of other disease such as diabetes or an underactive thyroid. Metabolism of cholesterol when the patient is affected by hypercholesterolemia: the deficient enzymes are actually transport proteins that transport LDL particles into the liver, and cholesterol accumulates in the bloodstream and other tissues.