描述
Ketorolac (also named Toradol) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used to relieve pain (analgesic), reduce fever (antipyretic) and swelling. Ketorolac can block prostaglandin synthesis by the action of inhibition of prostaglandin G/H synthase 1 and 2. Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway. Since prostaglandin is the messenger molecules in the process of inflammation; hence, inhibition of prostaglandin synthesis can reduce the pain, fever and inflammation.