(-)-Salsoline
IUPAC 名称
(1S)-7-methoxy-1-methyl-1,2,3,4-tetrahydroisoquinolin-6-ol
描述
(-)-Salsoline is a compound that crystallizes from alcohol solution, melts at 221 oC, soluble in hot alcohol and chloroform; used in medicine as an antihypertensive agent.
Salsoline as well as salsolinol were found in male alcoholic inpatients's urine and lumbar cerebrospinal fluid when patients were still intoxicated after a heavy alcohol debauch and after they had been inpatients and off alcohol for one week.There was a wide interindividual variation and no statistical significant difference in the levels between the first and second sampling in CSF or urine.[PMID: 6935920] [HMDB]
异构
COC1=CC2=C(CCN[C@H]2C)C=C1O
InChI标识符
InChI=1S/C11H15NO2/c1-7-9-6-11(14-2)10(13)5-8(9)3-4-12-7/h5-7,12-13H,3-4H2,1-2H3/t7-/m0/s1
键
YTPRLBGPGZHUPD-ZETCQYMHSA-N