4-Hydroxy tolbutamide
IUPAC 名称
3-butyl-1-[4-(hydroxymethyl)benzenesulfonyl]urea
描述
4-Hydroxy tolbutamide is a hydroxylation byproduct of tolbutamide. Tolbutamide is a first generation potassium channel blocker. It is a sulfonylurea oral hypoglycemic drug sold under the brand name Orinase. This drug may be used in the management of type II diabetes if diet alone is not effective. Tolbutamide stimulates the secretion of insulin by the pancreas. [HMDB]
异构
CCCCNC(=O)NS(=O)(=O)C1=CC=C(CO)C=C1
InChI标识符
InChI=1S/C12H18N2O4S/c1-2-3-8-13-12(16)14-19(17,18)11-6-4-10(9-15)5-7-11/h4-7,15H,2-3,8-9H2,1H3,(H2,13,14,16)
键
SJRHYONYKZIRPM-UHFFFAOYSA-N