描述
4-methoxyamphetamine, also known as 4-methoxyamphetamine hydrochloride or P-methoxy-alpha-methylphenethylamine, belongs to amphetamines and derivatives class of compounds. Those are organic compounds containing or derived from 1-phenylpropan-2-amine. 4-methoxyamphetamine is practically insoluble (in water) and a very strong basic compound (based on its pKa). 4-methoxyamphetamine can be found in potato, which makes 4-methoxyamphetamine a potential biomarker for the consumption of this food product. PMA has been found in tablets touted as MDMA (ecstasy) although its effects are markedly different compared to those of MDMA. The consequences of such deception have often included hospitalization and death for unwitting users. PMA is commonly synthesized from anethole, the flavor compound of anise and fennel, mainly because the starting material for MDMA, safrole, has become less available due to law enforcement action, causing illicit drug manufacturers to use anethole as an alternative . 4-Methoxyamphetamine is a seratogenic drug of the amphetamine class. The drug acts as a potent and selective serotonin releasing agent. It binds to alpha receptors to mediate these effects (DrugBank).
InChI标识符
InChI=1S/C10H15NO/c1-8(11)7-9-3-5-10(12-2)6-4-9/h3-6,8H,7,11H2,1-2H3