描述
7,4'-dihydroxyflavone, also known as 7-hydroxy-2-(4-hydroxyphenyl)-4h-chromen-4-one, is a member of the class of compounds known as flavones. Flavones are flavonoids with a structure based on the backbone of 2-phenylchromen-4-one (2-phenyl-1-benzopyran-4-one). Thus, 7,4'-dihydroxyflavone is considered to be a flavonoid lipid molecule. 7,4'-dihydroxyflavone is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). 7,4'-dihydroxyflavone can be found in alfalfa, broad bean, and fenugreek, which makes 7,4'-dihydroxyflavone a potential biomarker for the consumption of these food products. Like many other flavonoids, 4',7-dihydroxyflavone has been found to possess activity at the opioid receptors. Specifically, it acts as an antagonist of the μ-opioid receptor and, with lower affinity, of the κ- and δ-opioid receptors .