同义词

UniProt ID

Q9NZA1

UniProt名字

CLIC5_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

CLIC5

生物

Human

氨基酸序列

>lcl|BSEQ0009050|Chloride intracellular channel protein 5 MNDEDYSTIYDTIQNERTYEVPDQPEENESPHYDDVHEYLRPENDLYATQLNTHEYDFVS VYTIKGEETSLASVQSEDRGYLLPDEIYSELQEAHPGEPQEDRGISMEGLYSSTQDQQLC AAELQENGSVMKEDLPSPSSFTIQHSKAFSTTKYSCYSDAEGLEEKEGAHMNPEIYLFVK AGIDGESIGNCPFSQRLFMILWLKGVVFNVTTVDLKRKPADLHNLAPGTHPPFLTFNGDV KTDVNKIEEFLEETLTPEKYPKLAAKHRESNTAGIDIFSKFSAYIKNTKQQNNAALERGL TKALKKLDDYLNTPLPEEIDANTCGEDKGSRRKFLDGDELTLADCNLLPKLHVVKIVAKK YRNYDIPAEMTGLWRYLKNAYARDEFTNTCAADSEIELAYADVAKRLSRS

目标基因序列

残基数

410

分子量

46502.195

理论 pI

一般功能

Voltage-gated ion channel activity

具体功能

Required for normal hearing (PubMed:24781754). It is necessary for the formation of stereocilia in the inner ear and normal development of the organ of Corti (By similarity). Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. May play a role in the regulation of transepithelial ion absorption and secretion. Is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture (PubMed:15184393, PubMed:18028448, PubMed:20335315).

跨膜区

193-213

GenBank 蛋白质 ID

目标蛋白质序列

基因序列

>lcl|BSEQ0020848|Chloride intracellular channel protein 5 (CLIC5) ATGAATGACGAAGACTACAGCACCATCTATGACACAATCCAAAATGAGAGGACGTATGAG GTTCCAGACCAGCCAGAAGAAAATGAAAGTCCCCATTATGATGATGTCCATGAGTACTTA AGGCCAGAAAATGATTTATATGCCACTCAGCTGAATACCCATGAGTATGATTTTGTGTCA GTCTATACCATTAAGGGTGAAGAGACCAGCTTGGCCTCTGTCCAGTCAGAAGACAGAGGC TACCTCCTGCCTGATGAGATATACTCTGAACTCCAGGAGGCTCATCCAGGTGAGCCCCAG GAGGACAGGGGCATCTCAATGGAAGGGTTATATTCATCAACCCAGGACCAGCAACTCTGC GCAGCAGAACTCCAGGAGAATGGGAGTGTGATGAAGGAAGATCTGCCTTCTCCTTCAAGC TTCACCATTCAGCACAGTAAGGCCTTCTCTACCACCAAGTATTCCTGCTATTCTGATGCT GAAGGTTTGGAAGAAAAGGAGGGAGCTCACATGAACCCTGAGATTTACCTCTTTGTGAAG GCTGGAATCGATGGAGAAAGCATCGGCAACTGTCCTTTCTCTCAGCGCCTCTTCATGATC CTCTGGCTGAAAGGAGTCGTGTTCAATGTCACCACTGTGGATCTGAAAAGAAAGCCAGCT GACCTGCACAACCTAGCCCCCGGCACGCACCCGCCCTTCCTGACCTTCAACGGGGACGTG AAGACAGACGTCAATAAGATCGAGGAGTTCCTGGAGGAGACCTTGACCCCTGAAAAGTAC CCCAAACTGGCTGCAAAACACCGGGAATCCAACACAGCGGGCATCGACATCTTTTCCAAG TTTTCTGCCTACATCAAAAATACCAAGCAGCAGAACAATGCTGCTCTTGAAAGAGGCCTA ACCAAGGCTCTAAAGAAATTGGATGACTACCTGAACACCCCTCTACCAGAGGAGATTGAC GCCAACACTTGTGGGGAAGACAAGGGGTCCCGGCGCAAGTTCCTGGATGGGGATGAGCTG ACCCTGGCTGACTGCAATCTGTTGCCCAAGCTCCATGTGGTCAAGATTGTGGCCAAGAAA TACCGCAACTATGATATCCCGGCTGAGATGACAGGCCTGTGGCGGTACCTCAAGAACGCC TATGCCCGTGATGAGTTCACCAACACCTGTGCAGCTGACAGTGAGATCGAGTTGGCCTAC GCTGATGTCGCCAAACGCCTCAGCCGATCCTGA

GenBank 基因 ID

基因卡 ID

Genatlas ID

HGNC ID

HGNC:13517

染色体位置

6

轨迹

信号区域

Pdb标识

KEGG ID

hsa:53405

细胞的位置

Cytoplasm