同义词

Inward rectifier K(+) channel Kir5.1; Potassium channel, inwardly rectifying subfamily J member 16

UniProt ID

Q9NPI9

UniProt名字

KCJ16_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

KCNJ16

生物

Human

氨基酸序列

>lcl|BSEQ0017651|Inward rectifier potassium channel 16 MSYYGSSYHIINADAKYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVD IFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDLLNDPDITPCVDNVHSFTG AFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQ TIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYV PREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLHIEKAPPVR ESCTSDTKARRRSFSAVAIVSSCENPEETTTSATHEYRETPYQKALLTLNRISVESQM

目标基因序列

残基数

418

分子量

47948.585

理论 pI

一般功能

Inward rectifier potassium channel activity

具体功能

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance.

跨膜区

71-95 146-167

GenBank 蛋白质 ID

目标蛋白质序列

基因序列

>lcl|BSEQ0017652|Inward rectifier potassium channel 16 (KCNJ16) ATGAGCTATTACGGCAGCAGCTATCATATTATCAATGCGGACGCAAAATACCCAGGCTAC CCGCCAGAGCACATTATAGCTGAGAAGAGAAGAGCAAGAAGACGATTACTTCACAAAGAT GGCAGCTGTAATGTCTACTTCAAGCACATTTTTGGAGAATGGGGAAGCTATGTGGTTGAC ATCTTCACCACTCTTGTGGACACCAAGTGGCGCCATATGTTTGTGATATTTTCTTTATCT TATATTCTCTCGTGGTTGATATTTGGCTCTGTCTTTTGGCTCATAGCCTTTCATCATGGC GATCTATTAAATGATCCAGACATCACACCTTGTGTTGACAACGTCCATTCTTTCACAGGG GCCTTTTTGTTCTCCCTAGAGACCCAAACCACCATAGGATATGGTTATCGCTGTGTTACT GAAGAATGTTCTGTGGCCGTGCTCATGGTGATCCTCCAGTCCATCTTAAGTTGCATCATA AATACCTTTATCATTGGAGCTGCCTTGGCCAAAATGGCAACTGCTCGAAAGAGAGCCCAA ACCATTCGTTTCAGCTACTTTGCACTTATAGGTATGAGAGATGGGAAGCTTTGCCTCATG TGGCGCATTGGTGATTTTCGGCCAAACCACGTGGTAGAAGGAACAGTTAGAGCCCAACTT CTCCGCTATACAGAAGACAGTGAAGGGAGGATGACGATGGCATTTAAAGACCTCAAATTA GTCAACGACCAAATCATCCTGGTCACCCCGGTAACTATTGTCCATGAAATTGACCATGAG AGCCCTCTGTATGCCCTTGACCGCAAAGCAGTAGCCAAAGATAACTTTGAGATTTTGGTG ACATTTATCTATACTGGTGATTCCACTGGAACATCTCACCAATCTAGAAGCTCCTATGTT CCCCGAGAAATTCTCTGGGGCCATAGGTTTAATGATGTCTTGGAAGTTAAGAGGAAGTAT TACAAAGTGAACTGCTTACAGTTTGAAGGAAGTGTGGAAGTATATGCCCCCTTTTGCAGT GCCAAGCAATTGGACTGGAAAGACCAGCAGCTCCACATAGAAAAAGCACCACCAGTTCGA GAATCCTGCACGTCGGACACCAAGGCGAGACGAAGGTCATTTAGTGCAGTTGCCATTGTC AGCAGCTGTGAAAACCCTGAGGAGACCACCACTTCCGCCACACATGAATATAGGGAAACA CCTTATCAGAAAGCTCTCCTGACTTTAAACAGAATCTCTGTAGAATCCCAAATGTAG

GenBank 基因 ID

基因卡 ID

Genatlas ID

HGNC ID

HGNC:6262

染色体位置

17

轨迹

信号区域

Pdb标识

KEGG ID

hsa:3773

细胞的位置

Membrane