同义词

DNA-directed RNA polymerase I subunit E; PAF53; PRAF1; RNA polymerase I subunit A49; RNA polymerase I-associated factor 1; RNA polymerase I-associated factor 53

UniProt ID

Q9GZS1

UniProt名字

RPA49_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

POLR1E

生物

Human

氨基酸序列

>lcl|BSEQ0009190|DNA-directed RNA polymerase I subunit RPA49 MYQASAVSLLPRDIPSCHSPSPGFSHLPTSSSQLAPDLLQFPLGQDPSFLAIPILTLPPS DSLVPPYIVWYIVWPSALISFLGCTLTVQFSNGKLQSPGNMRFTLYENKDSTNPRKRNQR ILAAETDRLSYVGNNFGTGALKCNTLCRHFVGILNKTSGQMEVYDAELFNMQPLFSDVSV ESELALESQTKTYREKMDSCIEAFGTTKQKRALNTRRMNRVGNESLNRAVAKAAETIIDT KGVTALVSDAIHNDLQDDSLYLPPCYDDAAKPEDVYKFEDLLSPAEYEALQSPSEAFRNV TSEEILKMIEENSHCTFVIEALKSLPSDVESRDRQARCIWFLDTLIKFRAHRVVKRKSAL GPGVPHIINTKLLKHFTCLTYNNGRLRNLISDSMKAKITAYVIILALHIHDFQIDLTVLQ RDLKLSEKRMMEIAKAMRLKISKRRVSVAAGSEEDHKLGTLSLPLPPAQTSDRLAKRRKI T

目标基因序列

残基数

481

分子量

53961.43

理论 pI

一般功能

Dna-directed rna polymerase activity

具体功能

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF (By similarity).

跨膜区

GenBank 蛋白质 ID

目标蛋白质序列

基因序列

>lcl|BSEQ0013661|DNA-directed RNA polymerase I subunit RPA49 (POLR1E) ATGATGCTGAATTGTTCAACATGCAGCCACTATTTTCAGGTCTTTCACCAAGAAAGCAAA ATTATTTTCTGGAAAGAGCCAAGGACTTGTTTTCTAATCCTGTCTCTGCCACTACCTGGT GAACTGACCTGGGATGTATCAGTTGAGAGTGAACTGGCGCTAGAGAGTCAGACCAAAACT TACAGAGAAAAGATGGATTCTTGTATTGAAGCCTTTGGTACCACCAAACAGAAGCGAGCT CTGAACACCAGGAGAATGAACAGAGTTGGCAATGAATCTTTGAATCGTGCAGTGGCTAAA GCTGCAGAGACTATCATTGATACGAAGGGTGTGACTGCTCTGGTCAGCGATGCTATCCAC AATGACTTGCAAGATGACTCCCTCTACCTTCCTCCCTGCTATGATGATGCAGCCAAGCCT GAAGACGTGTATAAATTTGAAGATCTTCTTTCCCCTGCGGAGTATGAAGCTCTTCAGAGC CCATCTGAAGCTTTCAGGAACGTCACGTCAGAAGAAATACTGAAGATGATTGAGGAGAAC AGCCATTGCACCTTTGTCATAGAAGCGTTGAAGTCTTTGCCATCAGATGTGGAGAGCCGA GACCGCCAGGCCCGATGCATATGGTTTCTGGATACCCTCATCAAATTTCGAGCTCATAGG GTAGTTAAGCGGAAAAGTGCTCTGGGACCTGGAGTTCCCCACATCATCAACACCAAACTG CTGAAGCACTTTACTTGCTTGACCTACAACAATGGCAGATTACGGAACTTAATTTCGGAT TCTATGAAGGCGAAGATTACTGCATATGTGATCATACTTGCCTTGCACATACATGACTTC CAAATTGACCTGACAGTGTTACAGAGGGACTTGAAGCTCAGTGAGAAAAGGATGATGGAG ATAGCCAAAGCCATGAGGCTGAAGATCTCCAAAAGAAGGGTGTCTGTGGCCGCCGGCAGT GAAGAAGATCACAAACTGGGCACCCTGTCCCTCCCGCTGCCTCCAGCCCAGACCTCAGAC CGCCTGGCAAAGCGGAGGAAGATTACCTAG

GenBank 基因 ID

基因卡 ID

Genatlas ID

HGNC ID

HGNC:17631

染色体位置

9

轨迹

信号区域

Pdb标识

KEGG ID

hsa:64425

细胞的位置

Nucleus