Histone H2B type 1-M
同义词
H2B/e; H2BFE; Histone H2B.e
氨基酸序列
>lcl|BSEQ0013511|Histone H2B type 1-M
MPEPVKSAPVPKKGSKKAINKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAM
GIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVT
KYTSSK
具体功能
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
基因序列
>lcl|BSEQ0013512|Histone H2B type 1-M (HIST1H2BM)
ATGCCTGAACCAGTCAAATCTGCTCCAGTCCCTAAAAAAGGCTCCAAGAAGGCCATTAAC
AAGGCTCAGAAGAAGGATGGAAAGAAGCGCAAACGCAGCCGCAAGGAGAGCTACTCTGTG
TATGTGTACAAGGTGCTGAAGCAGGTCCACCCCGACACCGGCATCTCTTCCAAGGCTATG
GGAATCATGAACTCCTTCGTCAACGACATCTTTGAGCGTATCGCCGGAGAAGCGTCACGC
CTGGCGCATTACAACAAGCGCTCGACCATCACTTCGAGGGAGATCCAGACGGCCGTGCGC
CTACTGCTACCCGGGGAATTGGCCAAGCACGCCGTGTCCGAGGGCACCAAGGCCGTCACC
AAGTATACCAGCTCCAAGTGA