Histone H2B type 1-H
同义词
H2B/j; H2BFJ; Histone H2B.j
氨基酸序列
>lcl|BSEQ0013509|Histone H2B type 1-H
MPDPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAM
GIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVT
KYTSSK
具体功能
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
基因序列
>lcl|BSEQ0013510|Histone H2B type 1-H (HIST1H2BH)
ATGCCTGATCCAGCTAAGTCCGCTCCCGCCCCGAAGAAGGGCTCCAAGAAGGCGGTGACC
AAGGCGCAGAAGAAGGATGGCAAGAAGCGTAAACGCAGCCGCAAGGAGAGCTACTCCGTA
TACGTTTACAAGGTGCTGAAGCAAGTCCACCCCGACACCGGCATCTCCTCCAAAGCCATG
GGGATCATGAATTCCTTTGTCAACGATATCTTCGAGCGCATCGCCGGCGAGGCTTCCCGC
CTGGCTCATTACAACAAGCGTTCGACCATCACCTCCAGGGAGATCCAGACAGCCGTGCGC
CTGCTGCTGCCTGGGGAACTGGCCAAGCACGCCGTGTCCGAGGGCACTAAGGCCGTCACC
AAGTACACCAGCTCCAAATAA