Sodium channel subunit beta-4,目标的细节

Sodium channel subunit beta-4

同义词

UniProt ID

Q8IWT1

UniProt名字

SCN4B_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

SCN4B

生物

Human

氨基酸序列

>lcl|BSEQ0006993|Sodium channel subunit beta-4 MPGAGDGGKAPARWLGTGLLGLFLLPVTLSLEVSVGKATDIYAVNGTEILLPCTFSSCFG FEDLHFRWTYNSSDAFKILIEGTVKNEKSDPKVTLKDDDRITLVGSTKEKMNNISIVLRD LEFSDTGKYTCHVKNPKENNLQHHATIFLQVVDRLEEVDNTVTLIILAVVGGVIGLLILI LLIKKLIIFILKKTREKKKECLVSSSGNDNTENGLPGSKAEEKPPSKV

目标基因序列

残基数

228

分子量

24968.755

理论 pI

7.45

一般功能

Voltage-gated sodium channel activity involved in cardiac muscle cell action potential

具体功能

Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation. Modulates the suceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom.

跨膜区

163-183

GenBank 蛋白质 ID

27465047

目标蛋白质序列

基因序列

>lcl|BSEQ0017169|Sodium channel subunit beta-4 (SCN4B) ATGCCCGGGGCTGGGGACGGAGGCAAAGCCCCGGCGAGATGGCTGGGCACTGGGCTTTTG GTGGAAGAAGTGGACAACACAGTGACACTCATCATCCTGGCTGTCGTGGGCGGGGTCATC GGGCTCCTCATCCTCATCCTGCTGATCAAGAAACTCATCATCTTCATCCTGAAGAAGACT CGGGAGAAGAAGAAGGAGTGTCTCGTGAGCTCCTCGGGGAATGACAACACGGAGAACGGC TTGCCTGGCTCCAAGGCAGAGGAGAAACCACCTTCAAAAGTGTGA

GenBank 基因 ID

AY149967

基因卡 ID

Genatlas ID

HGNC ID

HGNC:10592

染色体位置

11

轨迹

11q23.3

信号区域

2022/1/30 0:00:00