同义词

H3F2; H3FM; Histone H3/m; Histone H3/o

UniProt ID

Q71DI3

UniProt名字

H32_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

HIST2H3A

生物

Human

氨基酸序列

>lcl|BSEQ0013430|Histone H3.2 MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTE LLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTI MPKDIQLARRIRGERA

目标基因序列

残基数

136

分子量

15387.865

理论 pI

一般功能

Histone binding

具体功能

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

跨膜区

GenBank 蛋白质 ID

目标蛋白质序列

基因序列

>lcl|BSEQ0013431|Histone H3.2 (HIST2H3A) ATGGCCCGTACTAAGCAGACTGCTCGCAAGTCGACCGGCGGCAAGGCCCCGAGGAAGCAG CTGGCCACCAAGGCGGCCCGCAAGAGCGCGCCGGCCACGGGCGGGGTGAAGAAGCCGCAC CGCTACCGGCCCGGCACCGTAGCCCTGCGGGAGATCCGGCGCTACCAGAAGTCCACGGAG CTGCTGATCCGCAAGCTGCCCTTCCAGCGGCTGGTACGCGAGATCGCGCAGGACTTTAAG ACGGACCTGCGCTTCCAGAGCTCGGCCGTGATGGCGCTGCAGGAGGCCAGCGAGGCCTAC CTGGTGGGGCTGTTCGAAGACACGAACCTGTGCGCCATCCACGCCAAGCGCGTGACCATT ATGCCCAAGGACATCCAGCTGGCCCGCCGCATCCGTGGAGAGCGGGCTTAA

GenBank 基因 ID

基因卡 ID

Genatlas ID

HGNC ID

HGNC:20505

染色体位置

1

轨迹

信号区域

Pdb标识

2IIJ; 2X4W; 2X4X; 2X4Y; 3AV1; 3DB3; 3MO8; 3QO2; 3R93; 4MZF; 4MZG; 4MZH; 4OUC; 5BO0

KEGG ID

hsa:126961

细胞的位置

Nucleus