同义词

AGS2; Aicardi-Goutieres syndrome 2 protein; Deleted in lymphocytic leukemia 8; DLEU8; Ribonuclease HI subunit B; RNase H2 subunit B

UniProt ID

Q5TBB1

UniProt名字

RNH2B_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

RNASEH2B

生物

Human

氨基酸序列

>lcl|BSEQ0009183|Ribonuclease H2 subunit B MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQL FEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDN VFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKT NNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSAS LPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTF FGVKNKKKIGKV

目标基因序列

残基数

312

分子量

35138.455

理论 pI

一般功能

Rna-dna hybrid ribonuclease activity

具体功能

Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.

跨膜区

GenBank 蛋白质 ID

目标蛋白质序列

基因序列

>lcl|BSEQ0013658|Ribonuclease H2 subunit B (RNASEH2B) ATGGCCGCTGGCGTGGACTGCGGGGACGGGGTTGGCGCCCGGCAGCACGTGTTCCTGGTT TCAGAATATTTAAAAGATGCTTCAAAGAAGATGAAAAATGGGCTAATGTTTGTAAAACTG GTTAACCCCTGTTCAGGAGAAGGAGCCATTTACTTGTTCAATATGTGTCTACAGCAGCTG TTTGAAGTAAAAGTTTTCAAGGAAAAACACCATTCTTGGTTTATAAATCAATCAGTTCAA TCAGGAGGTCTTCTCCATTTTGCCACACCTGTGGATCCTCTATTTCTGCTTCTCCACTAC CTCATAAAGGCTGATAAGGAGGGGAAGTTTCAGCCCCTTGATCAAGTTGTGGTGGATAAC GTGTTTCCAAATTGCATCTTGTTGCTGAAACTTCCTGGACTTGAGAAGTTACTTCATCAT GTGACAGAGGAAAAAGGTAATCCAGAAATAGACAACAAGAAATATTACAAGTACAGCAAA GAGAAGACATTAAAGTGGCTGGAAAAAAAGGTTAATCAAACTGTGGCAGCATTAAAAACC AATAATGTGAATGTCAGTTCCCGGGTACAGTCAACTGCATTTTTCTCTGGTGACCAAGCT TCCACTGACAAGGAAGAGGATTATATTCGTTATGCCCATGGTCTGATATCTGACTACATC CCTAAAGAATTAAGTGATGACTTATCTAAATACTTAAAGCTTCCAGAACCTTCAGCCTCA TTGCCAAATCCTCCATCAAAGATGGCAGCACAAAGACAGAAAAGGGGCAAGTGA

GenBank 基因 ID

基因卡 ID

Genatlas ID

HGNC ID

HGNC:25671

染色体位置

13

轨迹

信号区域

Pdb标识

3P56; 3P87; 3PUF

KEGG ID

hsa:79621

细胞的位置

Nucleus