同义词

2.5.1.18; Glutathione S-transferase A3-3; GST class-alpha member 3

UniProt ID

Q16772

UniProt名字

GSTA3_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

GSTA3

生物

Human

氨基酸序列

>lcl|BSEQ0001614|Glutathione S-transferase A3 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF

目标基因序列

残基数

222

分子量

25301.355

理论 pI

9.69

一般功能

Glutathione transferase activity

具体功能

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes isomerization reactions that contribute to the biosynthesis of steroid hormones. Efficiently catalyze obligatory double-bond isomerizations of delta(5)-androstene-3,17-dione and delta(5)-pregnene-3,20-dione, precursors to testosterone and progesterone, respectively.

跨膜区

GenBank 蛋白质 ID

951352

目标蛋白质序列

基因序列

>lcl|BSEQ0010569|Glutathione S-transferase A3 (GSTA3) ATGGCAGGGAAGCCCAAGCTTCACTACTTCAATGGACGGGGCAGAATGGAGCCCATCCGG TGGCTCTTGGCTGCAGCTGGAGTGGAGTTTGAAGAGAAATTTATAGGATCTGCAGAAGAT TTGGGAAAGTTAAGAAATGATGGGAGTTTGATGTTCCAGCAAGTACCAATGGTTGAGATT GATGGGATGAAGTTGGTACAGACCAGAGCCATTCTCAACTACATTGCCAGCAAATACAAC CTCTACGGGAAAGACATAAAGGAGAGAGCCCTAATTGATATGTATACAGAAGGTATGGCA GATTTGAATGAAATGATCCTTCTTCTGCCCTTATGTCGACCTGAGGAAAAAGATGCCAAG ATTGCCTTGATCAAAGAGAAAACAAAAAGTCGCTATTTCCCTGCCTTCGAAAAAGTGTTA CAGAGCCATGGACAAGACTACCTTGTTGGCAACAAGCTGAGCCGGGCTGACATTAGCCTG GTGGAACTTCTCTACTATGTGGAAGAGCTTGACTCCAGCCTTATCTCCAACTTCCCTCTG CTGAAGGCCCTGAAAACCAGAATCAGCAACCTGCCCACGGTGAAGAAGTTTCTACAGCCT GGCAGCCCAAGGAAGCCTCCCGCAGATGCAAAAGCTTTAGAAGAAGCCAGAAAGATTTTC AGGTTTTAA

GenBank 基因 ID

L13275

基因卡 ID

Genatlas ID

GSTA3

HGNC ID

HGNC:4628

染色体位置

6

轨迹

6p12.1

信号区域

Pdb标识

1TDI; 2VCV

KEGG ID

hsa:2940

细胞的位置

Cytoplasm