同义词

H3/g; H3/t; H3FT

UniProt ID

Q16695

UniProt名字

H31T_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

HIST3H3

生物

Human

氨基酸序列

>lcl|BSEQ0020821|Histone H3.1t MARTKQTARKSTGGKAPRKQLATKVARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTE LLIRKLPFQRLMREIAQDFKTDLRFQSSAVMALQEACESYLVGLFEDTNLCVIHAKRVTI MPKDIQLARRIRGERA

目标基因序列

残基数

136

分子量

15508.105

理论 pI

一般功能

Histone binding

具体功能

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

跨膜区

GenBank 蛋白质 ID

目标蛋白质序列

基因序列

>lcl|BSEQ0020822|Histone H3.1t (HIST3H3) ATGGCCCGAACCAAGCAGACTGCGCGCAAGTCAACGGGTGGCAAGGCGCCGCGCAAGCAG CTGGCCACCAAGGTGGCTCGCAAGAGCGCACCTGCCACTGGCGGCGTGAAGAAGCCGCAC CGCTACCGGCCCGGCACGGTGGCGCTTCGCGAGATCCGCCGCTACCAGAAGTCCACTGAG CTGCTAATCCGCAAGTTGCCCTTCCAGCGGCTGATGCGCGAGATCGCTCAGGACTTTAAG ACCGACCTGCGCTTCCAGAGCTCGGCCGTGATGGCGCTGCAGGAGGCGTGCGAGTCTTAC CTGGTGGGGCTGTTTGAGGACACCAACCTGTGTGTCATCCATGCCAAACGGGTCACCATC ATGCCTAAGGACATCCAGCTGGCACGCCGTATCCGCGGGGAGCGGGCCTAG

GenBank 基因 ID

基因卡 ID

Genatlas ID

HGNC ID

HGNC:4778

染色体位置

1

轨迹

信号区域

Pdb标识

2V1D; 2YBP; 2YBS; 3A6N; 3T6R; 4V2V; 4V2W

KEGG ID

hsa:8290

细胞的位置

Nucleus