同义词

3.6.3.8; Plasma membrane calcium ATPase isoform 2; Plasma membrane calcium pump isoform 2; PMCA2

UniProt ID

Q01814

UniProt名字

AT2B2_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

ATP2B2

生物

Human

氨基酸序列

>lcl|BSEQ0008771|Plasma membrane calcium-transporting ATPase 2 MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD KKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAMEMQ PLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS SPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL

目标基因序列

残基数

1243

分子量

136875.18

理论 pI

一般功能

Protein c-terminus binding

具体功能

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell.

跨膜区

95-115 153-173 391-410 444-461 876-895 906-926 947-969 988-1009 1029-1050 1061-1082

GenBank 蛋白质 ID

目标蛋白质序列

基因序列

>lcl|BSEQ0021877|Plasma membrane calcium-transporting ATPase 2 (ATP2B2) ATGGGTGACATGACCAACAGCGACTTTTACTCCAAAAACCAAAGAAATGAGTCGAGCCAT GGGGGCGAGTTCGGGTGCACAATGGAGGAGCTCCGCTCCCTCATGGAGCTGCGGGGCACT GAGGCTGTGGTCAAGATCAAGGAGACTTATGGGGACACCGAAGCCATCTGCCGGCGCCTC AAAACCTCACCTGTTGAAGGTTTGCCGGGCACCGCTCCAGACCTGGAAAAGAGAAAGCAA ATTTTTGGGCAAAACTTTATACCTCCAAAGAAGCCAAAAACCTTCCTGCAGCTCGTGTGG GAGGCGCTGCAGGACGTGACGCTCATCATCCTGGAGATTGCCGCCATCATCTCCCTGGGG CTGTCCTTCTACCACCCGCCCGGCGAGGGCAACGAAGGATGTGCGACGGCCCAGGGTGGG GCAGAGGATGAAGGAGAGGCAGAGGCAGGTTGGATCGAGGGGGCCGCCATTCTCCTCTCA GTTATCTGTGTGGTCCTGGTCACGGCCTTCAATGACTGGAGCAAAGAGAAACAGTTCCGG GGCCTGCAGAGCCGCATCGAGCAGGAACAGAAATTTACCGTGGTCCGGGCTGGCCAGGTG GTCCAGATCCCTGTGGCTGAGATCGTGGTTGGGGACATAGCCCAGGTCAAATATGGTGAC CTCCTCCCTGCCGACGGCCTCTTCATCCAGGGCAATGACCTCAAGATTGATGAAAGCTCC CTAACTGGAGAGTCTGACCAGGTGCGCAAGTCCGTGGACAAGGACCCCATGCTGCTGTCA GGAACCCACGTGATGGAGGGCTCAGGACGGATGTTGGTGACTGCTGTGGGTGTGAACTCT CAGACTGGCATCATCTTTACCCTCCTGGGGGCTGGTGGTGAAGAGGAAGAGAAGAAAGAC AAAAAAGGTGTGAAGAAGGGGGATGGCCTTCAGCTACCAGCAGCAGACGGTGCGGCAGCT TCAAATGCTGCAGATAGTGCGAATGCCAGCCTAGTCAATGGTAAAATGCAGGATGGCAAT GTGGACGCCAGCCAGAGCAAAGCCAAACAACAGGACGGGGCAGCCGCCATGGAGATGCAG CCCCTCAAGAGTGCCGAGGGCGGCGACGCTGACGACAGGAAGAAGGCCAGCATGCACAAG AAGGAGAAGTCCGTGCTGCAGGGCAAGCTCACCAAGCTGGCTGTGCAGATCGGGAAGGCG GGCTTGGTGATGTCAGCCATCACGGTGATCATCCTGGTGCTCTACTTCACTGTGGACACC TTCGTGGTCAACAAGAAGCCGTGGCTGCCTGAGTGCACGCCCGTCTACGTGCAGTACTTT GTCAAGTTCTTCATCATTGGCGTGACGGTGCTGGTGGTCGCCGTGCCCGAGGGGCTCCCT CTGGCCGTCACCATCTCGTTGGCCTATTCGGTGAAGAAAATGATGAAGGACAACAACCTG GTACGCCACCTGGATGCCTGTGAGACCATGGGCAATGCCACAGCCATCTGCTCAGACAAG ACAGGCACGCTGACCACCAATCGCATGACAGTGGTACAGGCCTATGTCGGCGACGTCCAC TATAAAGAGATCCCCGACCCCAGCTCCATCAACACCAAGACCATGGAGCTGCTGATCAAT GCCATCGCCATCAACAGCGCCTACACCACCAAGATTCTGCCCCCAGAGAAGGAGGGCGCC CTGCCTCGGCAGGTGGGCAACAAGACGGAGTGCGGCCTGCTGGGCTTCGTGCTGGACCTG AAGCAGGACTACGAGCCCGTGCGCAGCCAGATGCCAGAGGAGAAGTTGTACAAAGTGTAC ACCTTCAACTCCGTGCGCAAGTCCATGAGCACTGTCATCAAGCTGCCCGACGAGAGCTTC CGCATGTACAGCAAGGGGGCTTCTGAGATCGTGCTCAAGAAGTGCTGCAAAATCCTCAAT GGGGCGGGAGAGCCTCGTGTCTTCCGGCCCCGCGACCGGGACGAGATGGTAAAGAAGGTG ATTGAGCCCATGGCTTGCGATGGGCTCCGCACTATCTGCGTGGCCTACCGCGACTTCCCC AGCAGCCCGGAGCCGGACTGGGACAATGAGAATGACATCCTCAACGAACTCACCTGCATC TGCGTGGTGGGCATCGAGGACCCGGTGCGGCCAGAGGTCCCAGAAGCCATCCGCAAGTGC CAGCGGGCAGGCATCACGGTCCGCATGGTCACTGGCGACAATATCAACACGGCTCGGGCC ATCGCCATCAAGTGTGGCATCATCCATCCTGGGGAGGACTTTCTGTGCCTCGAGGGCAAG GAGTTCAACAGGAGGATCCGCAACGAGAAGGGGGAGATTGAGCAGGAGCGAATTGACAAG ATCTGGCCAAAGCTGCGGGTGCTGGCTCGCTCCTCCCCAACGGACAAGCATACCCTGGTT AAAGGCATCATCGACAGCACACACACTGAGCAGCGGCAGGTGGTGGCCGTGACGGGGGAC GGGACCAACGACGGGCCTGCACTCAAGAAGGCCGACGTGGGCTTCGCCATGGGCATCGCA GGCACTGACGTGGCCAAGGAGGCCTCAGACATCATCCTGACAGACGACAATTTCAGCAGC ATCGTCAAGGCAGTGATGTGGGGCCGCAACGTCTATGACAGCATCTCCAAATTCTTGCAG TTCCAGCTCACCGTCAACGTGGTGGCCGTGATTGTGGCCTTCACAGGCGCCTGCATCACG CAGGACTCCCCTCTGAAGGCCGTGCAGATGCTCTGGGTGAACCTCATCATGGACACGTTT GCCTCGCTGGCACTGGCCACTGAGCCGCCCACGGAGACCCTGCTGCTGAGGAAGCCGTAC GGCCGCAACAAGCCGCTCATCTCCAGGACCATGATGAAGAACATCCTGGGCCATGCTGTC TACCAGCTTGCCCTCATCTTCACCCTGCTCTTTGTTGGCGAGAAGATGTTCCAGATCGAC AGCGGGAGGAACGCGCCCCTGCATTCGCCACCCTCAGAACATTACACCATCATCTTCAAC ACCTTCGTCATGATGCAGCTCTTCAACGAGATCAACGCCCGCAAGATCCACGGCGAGCGC AATGTCTTTGACGGCATCTTCCGGAACCCCATCTTCTGCACCATCGTGCTGGGCACCTTT GCCATCCAGATAGTGATCGTGCAGTTTGGAGGGAAGCCATTCAGCTGCTCTCCACTGCAG CTGGACCAGTGGATGTGGTGCATATTCATTGGGTTAGGAGAGCTCGTTTGGGGCCAGGTC ATCGCCACCATCCCGACCAGCAGACTCAAGTTCCTCAAGGAGGCAGGCAGGCTCACACAG AAGGAGGAGATCCCGGAGGAGGAGCTCAACGAGGACGTGGAGGAGATCGACCACGCGGAG CGGGAGCTGCGGCGGGGCCAGATCCTGTGGTTCCGAGGCCTGAATCGGATCCAGACACAG ATCCGCGTCGTGAAGGCGTTCCGTAGCTCTCTCTATGAAGGTTTAGAAAAGCCTGAATCT CGAACCTCCATCCATAACTTCATGGCTCATCCTGAATTCCGGATCGAAGATTCCCAGCCC CACATCCCCCTCATTGATGACACCGACCTGGAAGAAGATGCCGCGCTCAAGCAGAACTCG AGCCCGCCGTCATCCCTCAACAAGAACAACAGCGCCATCGACAGTGGGATCAACCTGACG ACCGACACAAGCAAATCAGCTACCTCTTCAAGTCCAGGGAGCCCCATCCACAGCCTGGAG ACGTCGCTTTAG

GenBank 基因 ID

基因卡 ID

Genatlas ID

HGNC ID

HGNC:815

染色体位置

3

轨迹

信号区域

Pdb标识

KEGG ID

hsa:491

细胞的位置

Cell junction