同义词

CYC

UniProt ID

P99999

UniProt名字

CYC_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

CYCS

生物

Human

氨基酸序列

>lcl|BSEQ0010707|Cytochrome c MGDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGYSYTAANKNKGIIW GEDTLMEYLENPKKYIPGTKMIFVGIKKKEERADLIAYLKKATNE

目标基因序列

残基数

105

分子量

11748.69

理论 pI

10.16

一般功能

Metal ion binding

具体功能

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

跨膜区

GenBank 蛋白质 ID

181242

目标蛋白质序列

基因序列

>lcl|BSEQ0010708|Cytochrome c (CYCS) ATGGGTGATGTTGAGAAAGGCAAGAAGATTTTTATTATGAAGTGTTCCCAGTGCCACACC GTTGAAAAGGGAGGCAAGCACAAGACTGGGCCAAATCTCCATGGTCTCTTTGGGCGGAAG ACAGGTCAGGCCCCTGGATACTCTTACACAGCCGCCAATAAGAACAAAGGCATCATCTGG GGAGAGGATACACTGATGGAGTATTTGGAGAATCCCAAGAAGTACATCCCTGGAACAAAA ATGATCTTTGTCGGCATTAAGAAGAAGGAAGAAAGGGCAGACTTAATAGCTTATCTCAAA AAAGCTACTAATGAGTAA

GenBank 基因 ID

M22877

基因卡 ID

Genatlas ID

CYCS

HGNC ID

HGNC:19986

染色体位置

7

轨迹

7p15.2

信号区域

Pdb标识

1J3S; 3NWV; 3ZCF; 3ZOO

KEGG ID

hsa:54205

细胞的位置

Mitochondrion intermembrane space