同义词

DNA-directed RNA polymerase III subunit L; RNA polymerase II 7.6 kDa subunit; RNA polymerases I, II, and III subunit ABC5; RPB10 homolog; RPB7.6

UniProt ID

P62875

UniProt名字

RPAB5_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

POLR2L

生物

Human

氨基酸序列

>lcl|BSEQ0013576|DNA-directed RNA polymerases I, II, and III subunit RPABC5 MIIPVRCFTCGKIVGNKWEAYLGLLQAEYTEGDALDALGLKRYCCRRMLLAHVDLIEKLL NYAPLEK

目标基因序列

残基数

67

分子量

7645.02

理论 pI

一般功能

Zinc ion binding

具体功能

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2L/RBP10 is part of the core element with the central large cleft (By similarity).

跨膜区

GenBank 蛋白质 ID

目标蛋白质序列

基因序列

>lcl|BSEQ0013577|DNA-directed RNA polymerases I, II, and III subunit RPABC5 (POLR2L) ATGATCATCCCTGTACGCTGCTTCACTTGTGGCAAGATCGTCGGCAACAAGTGGGAGGCT TACCTGGGGCTGCTGCAGGCCGAGTACACCGAGGGGGATGCGCTGGATGCCCTGGGCCTG AAGCGCTACTGCTGCCGCCGGATGCTGCTGGCCCACGTGGACCTGATCGAGAAGCTGCTC AATTATGCACCCCTGGAGAAGTGA

GenBank 基因 ID

基因卡 ID

Genatlas ID

HGNC ID

HGNC:9199

染色体位置

11

轨迹

信号区域

Pdb标识

KEGG ID

hsa:5441

细胞的位置

Nucleus