同义词

H2B/b; H2BFB; HIRA-interacting protein 2; HIRIP2; Histone H2B.1 B; Histone H2B.b

UniProt ID

P58876

UniProt名字

H2B1D_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

HIST1H2BD

生物

Human

氨基酸序列

>lcl|BSEQ0013503|Histone H2B type 1-D MPEPTKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAM GIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVT KYTSSK

目标基因序列

残基数

126

分子量

13936.065

理论 pI

一般功能

Dna binding

具体功能

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

跨膜区

GenBank 蛋白质 ID

目标蛋白质序列

基因序列

>lcl|BSEQ0013504|Histone H2B type 1-D (HIST1H2BD) ATGCCTGAACCTACCAAGTCTGCTCCTGCCCCAAAGAAGGGCTCCAAGAAGGCGGTGACT AAGGCTCAGAAGAAGGACGGGAAGAAGCGCAAGCGCAGCCGCAAGGAGAGCTATTCAGTG TATGTGTACAAGGTGCTGAAGCAGGTCCATCCCGACACCGGCATCTCTTCCAAGGCAATG GGGATCATGAATTCCTTCGTCAACGACATCTTCGAGCGCATCGCAGGCGAGGCTTCCCGC CTGGCGCATTACAACAAGCGCTCGACCATCACCTCCAGGGAGATCCAGACGGCCGTGCGC CTGCTGCTTCCGGGGGAGCTGGCCAAGCACGCCGTGTCGGAGGGCACCAAGGCCGTCACC AAGTACACCAGTTCCAAGTAA

GenBank 基因 ID

基因卡 ID

Genatlas ID

HGNC ID

HGNC:4747

染色体位置

6

轨迹

信号区域

Pdb标识

KEGG ID

hsa:3017

细胞的位置

Nucleus