同义词

3.1.3.48; Neural-specific protein-tyrosine phosphatase; STEP; Striatum-enriched protein-tyrosine phosphatase

UniProt ID

P54829

UniProt名字

PTN5_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

PTPN5

生物

Human

氨基酸序列

>lcl|BSEQ0009003|Tyrosine-protein phosphatase non-receptor type 5 MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ TCEQYQFVHHVMSLYEKQLSHQSPE

目标基因序列

残基数

565

分子量

63537.53

理论 pI

一般功能

Protein tyrosine phosphatase activity

具体功能

May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors.

跨膜区

88-108 146-166

GenBank 蛋白质 ID

目标蛋白质序列

基因序列

>lcl|BSEQ0019698|Tyrosine-protein phosphatase non-receptor type 5 (PTPN5) ATGAATTATGAGGGAGCCAGGAGTGAGAGAGAGAACCACGCTGCTGATGACTCCGAGGGA GGGGCCCTGGACATGTGCTGCAGTGAGAGGCTACCGGGTCTCCCCCAGCCGATAGTGATG GAGGCACTGGACGAGGCTGAAGGGCTCCAGGACTCACAGAGAGAGATGCCGCCACCCCCT CCTCCCTCGCCGCCCTCAGATCCAGCTCAGAAGCCACCACCTCGAGGCGCTGGGAGCCAC TCCCTCACTGTCAGGAGCAGCCTGTGCCTGTTCGCTGCCTCACAGTTCCTGCTGGAACCC ACGGCCTGGCTTGACTCTGGGACGTGGGGAGTCCCCAGTCTGCTGCTGGTCTTTCTGTCC GTGGGCCTGGTCCTCGTTACCACCCTGGTGTGGCACCTCCTGAGGACACCCCCAGAGCCA CCCACCCCACTGCCCCCTGAGGACAGGCGCCAGTCAGTGAGCCGCCAGCCCTCCTTCACC TACTCAGAGTGGATGGAGGAGAAGATCGAGGATGACTTCCTGGACCTCGACCCGGTGCCC GAGACTCCTGTGTTTGATTGTGTGATGGACATCAAGCCTGAGGCTGACCCCACCTCACTC ACCGTCAAGTCCATGGGTCTGCAGGAGAGGAGGGGTTCCAATGTCTCCCTGACCCTGGAC ATGTGCACTCCGGGCTGCAACGAGGAGGGCTTTGGCTATCTCATGTCCCCACGTGAGGAG TCCGCCCGCGAGTACCTGCTCAGCGCCTCCCGTGTCCTCCAAGCAGAAGAGCTTCATGAA AAGGCCCTGGACCCTTTCCTGCTGCAGGCGGAATTCTTTGAAATCCCCATGAACTTTGTG GATCCGAAAGAGTACGACATCCCTGGGCTGGTGCGGAAGAACCGGTACAAAACCATACTT CCCAACCCTCACAGCAGAGTGTGTCTGACCTCACCAGACCCTGACGACCCTCTGAGTTCC TACATCAATGCCAACTACATCCGGGGCTATGGTGGGGAGGAGAAGGTGTACATCGCCACT CAGGGACCCATCGTCAGCACGGTCGCCGACTTCTGGCGCATGGTGTGGCAGGAGCACACG CCCATCATTGTCATGATCACCAACATCGAGGAGATGAACGAGAAATGCACCGAGTATTGG CCGGAGGAGCAGGTGGCGTACGACGGTGTTGAGATCACTGTGCAGAAAGTCATTCACACG GAGGATTACCGGCTGCGACTCATCTCCCTCAAGAGTGGGACTGAGGAGCGAGGCCTGAAG CATTACTGGTTCACATCCTGGCCCGACCAGAAGACCCCAGACCGGGCCCCCCCACTCCTG CACCTGGTGCGGGAGGTGGAGGAGGCAGCCCAGCAGGAGGGGCCCCACTGTGCCCCCATC ATCGTCCACTGCAGTGCAGGGATTGGGAGGACCGGCTGCTTCATTGCCACCAGCATCTGC TGCCAGCAGCTGCGGCAGGAGGGTGTGGTGGACATCCTGAAGACCACGTGCCAGCTCCGT CAGGACAGGGGCGGCATGATCCAGACATGCGAGCAGTACCAGTTTGTGCACCACGTCATG AGCCTCTACGAAAAGCAGCTGTCCCACCAGTCCCCAGAATGA

GenBank 基因 ID

基因卡 ID

Genatlas ID

HGNC ID

HGNC:9657

染色体位置

11

轨迹

信号区域

Pdb标识

2BIJ; 2BV5; 2CJZ

KEGG ID

hsa:84867

细胞的位置

Endoplasmic reticulum membrane