同义词

ADH water channel; AQP-2; AQP-CD; Aquaporin-CD; Collecting duct water channel protein; Water channel protein for renal collecting duct; WCH-CD

UniProt ID

P41181

UniProt名字

AQP2_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

AQP2

生物

Human

氨基酸序列

>lcl|BSEQ0013408|Aquaporin-2 MWELRSIAFSRAVFAEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLGIGTLVQALG HISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAVNA LSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHYTG CSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKGL EPDTDWEEREVRRRQSVELHSPQSLPRGTKA

目标基因序列

残基数

271

分子量

28837.17

理论 pI

一般功能

Water transmembrane transporter activity

具体功能

Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.

跨膜区

17-34 41-59 86-107 128-148 157-176 203-224

GenBank 蛋白质 ID

目标蛋白质序列

基因序列

>lcl|BSEQ0013409|Aquaporin-2 (AQP2) ATGTGGGAGCTCCGCTCCATAGCCTTCTCCAGGGCTGTGTTCGCAGAGTTCCTGGCCACA CTCCTCTTCGTCTTCTTTGGCCTCGGCTCTGCCCTCAACTGGCCACAGGCCCTGCCCTCT GTGCTACAGATTGCCATGGCGTTTGGCTTGGGTATTGGCACCCTGGTACAGGCTCTGGGC CACATAAGCGGGGCCCACATCAACCCTGCCGTGACTGTGGCCTGCCTGGTGGGCTGCCAC GTCTCCGTTCTCCGAGCCGCCTTCTACGTGGCTGCCCAGCTGCTGGGGGCTGTGGCCGGA GCCGCTCTGCTCCATGAGATCACGCCAGCAGACATCCGCGGGGACCTGGCTGTCAATGCT CTCAGCAACAGCACGACGGCTGGCCAGGCGGTGACTGTGGAGCTCTTCCTGACACTGCAG CTGGTGCTCTGCATCTTCGCCTCCACCGATGAGCGCCGCGGAGAGAACCCGGGCACCCCT GCTCTCTCCATAGGCTTCTCCGTGGCCCTGGGCCACCTCCTTGGGATCCATTACACCGGC TGCTCTATGAATCCTGCCCGCTCCCTGGCTCCAGCTGTCGTCACTGGCAAATTTGATGAC CACTGGGTCTTCTGGATCGGACCCCTGGTGGGCGCCATCCTGGGCTCCCTCCTCTACAAC TACGTGCTGTTTCCGCCAGCCAAGAGCCTGTCGGAGCGCCTGGCAGTGCTGAAGGGCCTG GAGCCGGACACCGATTGGGAGGAGCGCGAGGTGCGACGGCGGCAGTCGGTGGAGCTGCAC TCGCCGCAGAGCCTGCCACGGGGTACCAAGGCCTGA

GenBank 基因 ID

基因卡 ID

Genatlas ID

HGNC ID

HGNC:634

染色体位置

12

轨迹

信号区域

Pdb标识

4NEF; 4OJ2

KEGG ID

hsa:359

细胞的位置

Apical cell membrane