同义词

AQP-1; Aquaporin-CHIP; CHIP28; Urine water channel; Water channel protein for red blood cells and kidney proximal tubule

UniProt ID

P29972

UniProt名字

AQP1_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

AQP1

生物

Human

氨基酸序列

>lcl|BSEQ0001754|Aquaporin-1 MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSI ATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLT GNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGH LLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTD RVKVWTSGQVEEYDLDADDINSRVEMKPK

目标基因序列

残基数

269

分子量

28525.68

理论 pI

7.5

一般功能

Water transmembrane transporter activity

具体功能

Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.

跨膜区

8-36 49-66 95-115 137-155 167-183 208-228

GenBank 蛋白质 ID

180501

目标蛋白质序列

基因序列

>lcl|BSEQ0021277|Aquaporin-1 (AQP1) ATGCCTGGGGCTCGCCCCTTGCCTCTGGTCTTGGTACCCCAGAATACCCTGGCCTGGATG CAGCTGGATGCAAAGGCCCCAGCTCACCCCAGGCCTCTCCAGCTTCTAGGCAGAGTGGGG CCTGGGTCTAGGCAGCTGGCTGATGGTGTGAACTCGGGCCAGGGCCTGGGCATCGAGATC ATCGGGACCCTCCAGCTGGTGCTATGCGTGCTGGCTACTACCGACCGGAGGCGCCGTGAC CTTGGTGGCTCAGCCCCCCTTGCCATCGGCCTCTCTGTAGCCCTTGGACACCTCCTGGCT ATTGACTACACTGGCTGTGGGATTAACCCTGCTCGGTCCTTTGGCTCCGCGGTGATCACA CACAACTTCAGCAACCACTGGATTTTCTGGGTGGGGCCATTCATCGGGGGAGCCCTGGCT GTACTCATCTACGACTTCATCCTGGCCCCACGCAGCAGTGACCTCACAGACCGCGTGAAG GTGTGGACCAGCGGCCAGGTGGAGGAGTATGACCTGGATGCCGACGACATCAACTCCAGG GTGGAGATGAAGCCCAAATAG

GenBank 基因 ID

M77829

基因卡 ID

Genatlas ID

AQP1

HGNC ID

HGNC:633

染色体位置

7

轨迹

7p14

信号区域

Pdb标识

1FQY; 1H6I; 1IH5; 4CSK

KEGG ID

hsa:358

细胞的位置

Cell membrane