同义词

H1F2; Histone H1c; Histone H1d; Histone H1s-1

UniProt ID

P16403

UniProt名字

H12_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

HIST1H1C

生物

Human

氨基酸序列

>lcl|BSEQ0013479|Histone H1.2 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKV KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVA KPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK

目标基因序列

残基数

213

分子量

21364.57

理论 pI

一般功能

Poly(a) rna binding

具体功能

Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).

跨膜区

GenBank 蛋白质 ID

目标蛋白质序列

基因序列

>lcl|BSEQ0013480|Histone H1.2 (HIST1H1C) ATGTCCGAGACTGCTCCTGCCGCTCCCGCTGCCGCGCCTCCTGCGGAGAAGGCCCCTGTA AAGAAGAAGGCGGCCAAAAAGGCTGGGGGTACGCCTCGTAAGGCGTCTGGTCCCCCGGTG TCAGAGCTCATCACCAAGGCTGTGGCCGCCTCTAAAGAGCGTAGCGGAGTTTCTCTGGCT GCTCTGAAAAAAGCGTTGGCTGCCGCCGGCTATGATGTGGAGAAAAACAACAGCCGTATC AAACTTGGTCTCAAGAGCCTGGTGAGCAAGGGCACTCTGGTGCAAACGAAAGGCACCGGT GCTTCTGGCTCCTTTAAACTCAACAAGAAGGCAGCCTCCGGGGAAGCCAAGCCCAAGGTT AAAAAGGCGGGCGGAACCAAACCTAAGAAGCCAGTTGGGGCAGCCAAGAAGCCCAAGAAG GCGGCTGGCGGCGCAACTCCGAAGAAGAGCGCTAAGAAAACACCGAAGAAAGCGAAGAAG CCGGCCGCGGCCACTGTAACCAAGAAAGTGGCTAAGAGCCCAAAGAAGGCCAAGGTTGCG AAGCCCAAGAAAGCTGCCAAAAGTGCTGCTAAGGCTGTGAAGCCCAAGGCCGCTAAGCCC AAGGTTGTCAAGCCTAAGAAGGCGGCGCCCAAGAAGAAATAG

GenBank 基因 ID

基因卡 ID

Genatlas ID

HGNC ID

HGNC:4716

染色体位置

6

轨迹

信号区域

Pdb标识

KEGG ID

hsa:3006

细胞的位置

Nucleus