同义词

H2A.1; H2AFC; H2AFD; H2AFI; H2AFN; H2AFP; Histone H2A/p

UniProt ID

P0C0S8

UniProt名字

H2A1_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

HIST1H2AG

生物

Human

氨基酸序列

>lcl|BSEQ0019684|Histone H2A type 1 MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK TESHHKAKGK

目标基因序列

残基数

130

分子量

14091.375

理论 pI

一般功能

Enzyme binding

具体功能

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

跨膜区

GenBank 蛋白质 ID

目标蛋白质序列

基因序列

>lcl|BSEQ0019685|Histone H2A type 1 (HIST1H2AG) ATGTCTGGGCGTGGCAAGCAGGGAGGCAAAGCTCGCGCCAAGGCCAAGACCCGCTCTTCT CGGGCCGGGCTTCAGTTTCCCGTAGGCCGAGTGCATCGCCTGCTCCGCAAAGGCAACTAT GCGGAGCGGGTCGGTGCTGGAGCGCCGGTGTACCTGGCGGCGGTGCTGGAGTACCTGACC GCCGAGATCCTGGAGCTGGCTGGCAACGCGGCCCGCGACAACAAGAAGACTCGCATCATC CCGCGTCACCTCCAGCTGGCCATCCGCAACGATGAGGAGCTCAACAAGCTTCTGGGCAAA GTCACCATCGCACAGGGTGGCGTCCTGCCCAACATCCAGGCCGTGCTACTGCCCAAGAAG ACCGAGAGCCACCACAAGGCGAAGGGCAAGTAG

GenBank 基因 ID

基因卡 ID

Genatlas ID

HGNC ID

HGNC:4737

染色体位置

6

轨迹

信号区域

Pdb标识

4QYL

KEGG ID

hsa:8329

细胞的位置

Nucleus