同义词

H2B/r; H2BFR; Histone H2B.1; Histone H2B.r

UniProt ID

P06899

UniProt名字

H2B1J_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

HIST1H2BJ

生物

Human

氨基酸序列

>lcl|BSEQ0021424|Histone H2B type 1-J MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAM GIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVT KYTSAK

目标基因序列

残基数

126

分子量

13904.055

理论 pI

一般功能

Dna binding

具体功能

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.

跨膜区

GenBank 蛋白质 ID

目标蛋白质序列

基因序列

>lcl|BSEQ0021425|Histone H2B type 1-J (HIST1H2BJ) ATGCCAGAGCCAGCGAAGTCTGCTCCCGCCCCGAAAAAGGGCTCCAAGAAGGCGGTGACT AAGGCGCAGAAGAAAGACGGCAAGAAGCGCAAGCGCAGCCGCAAGGAGAGCTATTCCATC TATGTGTACAAGGTTCTGAAGCAGGTCCACCCTGACACCGGCATTTCGTCCAAGGCCATG GGCATCATGAATTCGTTTGTGAACGACATTTTCGAGCGCATCGCAGGTGAGGCTTCCCGC CTGGCGCATTACAACAAGCGCTCGACCATCACCTCCAGGGAGATCCAGACGGCCGTGCGC CTGCTGCTGCCTGGGGAGTTGGCCAAGCACGCCGTGTCCGAGGGTACTAAGGCCGTCACC AAGTACACCAGCGCTAAGTAA

GenBank 基因 ID

基因卡 ID

Genatlas ID

HGNC ID

HGNC:4761

染色体位置

6

轨迹

信号区域

Pdb标识

3A6N; 3AFA; 3AN2; 3AV1; 3AV2; 3AYW; 3AZE; 3AZF; 3AZG; 3AZH; 3AZI; 3AZJ; 3AZK; 3AZL; 3AZM; 3AZN; 3W96; 3W97; 3W98; 3W99; 3WA9; 3WAA; 3WTP; 4CAY; 5CPI; 5CPJ; 5CPK

KEGG ID

hsa:8970

细胞的位置

Nucleus