同义词

H2AFA; H2AFM; Histone H2A.2; Histone H2A/a; Histone H2A/m

UniProt ID

P04908

UniProt名字

H2A1B_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

HIST1H2AB

生物

Human

氨基酸序列

>lcl|BSEQ0019687|Histone H2A type 1-B/E MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLT AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKK TESHHKAKGK

目标基因序列

残基数

130

分子量

14135.385

理论 pI

一般功能

Dna binding

具体功能

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

跨膜区

GenBank 蛋白质 ID

目标蛋白质序列

基因序列

>lcl|BSEQ0019688|Histone H2A type 1-B/E (HIST1H2AB) ATGTCTGGACGTGGAAAGCAAGGCGGCAAAGCTCGGGCAAAAGCTAAAACGCGTTCTTCC AGGGCCGGTCTTCAGTTTCCAGTTGGCCGTGTGCACCGCCTCCTCCGCAAAGGCAACTAC TCCGAACGAGTCGGGGCCGGCGCTCCAGTGTACCTGGCAGCGGTGCTGGAATATCTGACG GCCGAGATCTTAGAGCTAGCTGGCAACGCGGCTCGCGACAATAAGAAGACCCGCATCATC CCGCGCCACCTGCAGCTAGCCATCCGCAACGACGAGGAGCTAAATAAGCTTCTAGGTCGC GTGACCATCGCGCAGGGCGGTGTCCTGCCCAACATCCAGGCCGTATTGCTGCCTAAGAAG ACGGAGAGCCACCATAAGGCCAAGGGCAAGTGA

GenBank 基因 ID

基因卡 ID

Genatlas ID

HGNC ID

HGNC:4734

染色体位置

6

轨迹

信号区域

Pdb标识

2CV5; 3A6N; 3AFA; 3AN2; 3AV1; 3AV2; 3AYW; 3AZE; 3AZF; 3AZG; 3AZH; 3AZI; 3AZJ; 3AZK; 3AZL; 3AZM; 3AZN; 3W96; 3W97; 3W98; 3W99; 3WKJ; 3WTP; 3X1S; 3X1V; 5CPI; 5CPJ; 5CPK

KEGG ID

hsa:3012

细胞的位置

Nucleus