同义词

3.1.3.48; PRL-3; PRL-R; PRL3; Protein-tyrosine phosphatase 4a3; Protein-tyrosine phosphatase of regenerating liver 3

UniProt ID

O75365

UniProt名字

TP4A3_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

PTP4A3

生物

Human

氨基酸序列

>lcl|BSEQ0008991|Protein tyrosine phosphatase type IVA 3 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM

目标基因序列

残基数

173

分子量

19534.69

理论 pI

一般功能

Protein tyrosine/serine/threonine phosphatase activity

具体功能

Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II.

跨膜区

GenBank 蛋白质 ID

目标蛋白质序列

基因序列

>lcl|BSEQ0013552|Protein tyrosine phosphatase type IVA 3 (PTP4A3) ATGGCTCGGATGAACCGCCCGGCCCCGGTGGAGGTGAGCTACAAACACATGCGCTTCCTC ATCACCCACAACCCCACCAACGCCACGCTCAGCACCTTCATTGAGGACCTGAAGAAGTAC GGGGCTACCACTGTGGTGCGTGTGTGTGAAGTGACCTATGACAAAACGCCGCTGGAGAAG GATGGCATCACCGTTGTGGACTGGCCGTTTGACGATGGGGCGCCCCCGCCCGGCAAGGTA GTGGAAGACTGGCTGAGCCTGGTGAAGGCCAAGTTCTGTGAGGCCCCCGGCAGCTGCGTG GCTGTGCACTGCGTGGCGGGCCTGGGCCGGAAGCGCCGCGGAGCCATCAACAGCAAGCAG CTCACCTACCTGGAGAAATACCGGCCCAAACAGAGGCTGCGGTTCAAAGACCCACACACG CACAAGACCCGGTGCTGCGTTATGTAG

GenBank 基因 ID

基因卡 ID

Genatlas ID

HGNC ID

HGNC:9636

染色体位置

8

轨迹

信号区域

Pdb标识

1R6H; 1V3A; 2MBC

KEGG ID

hsa:11156

细胞的位置

Cell membrane