同义词

UniProt ID

O60939

UniProt名字

SCN2B_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

SCN2B

生物

Human

氨基酸序列

>lcl|BSEQ0012528|Sodium channel subunit beta-2 MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNH KQFSLNWTYQECNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPE DEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVV KCVRRKKEQKLSTDDLKTEEEGKTDGEGNPDDGAK

目标基因序列

残基数

215

分子量

24325.69

理论 pI

6.35

一般功能

Voltage-gated sodium channel activity involved in cardiac muscle cell action potential

具体功能

Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier (By similarity).

跨膜区

160-180

GenBank 蛋白质 ID

3309111

目标蛋白质序列

基因序列

>lcl|BSEQ0012529|Sodium channel subunit beta-2 (SCN2B) ATGCACAGAGATGCCTGGCTACCTCGCCCTGCCTTCAGCCTCACGGGGCTCAGTCTCTTT TTCTCTTTGGTGCCACCAGGACGGAGCATGGAGGTCACAGTACCTGCCACCCTCAACGTC CTCAATGGCTCTGACGCCCGCCTGCCCTGCACCTTCAACTCCTGCTACACAGTGAACCAC AAACAGTTCTCCCTGAACTGGACTTACCAGGAGTGCAACAACTGCTCTGAGGAGATGTTC CTCCAGTTCCGCATGAAGATCATTAACCTGAAGCTGGAGCGGTTTCAAGACCGCGTGGAG TTCTCAGGGAACCCCAGCAAGTACGATGTGTCGGTGATGCTGAGAAACGTGCAGCCGGAG GATGAGGGGATTTACAACTGCTACATCATGAACCCCCCTGACCGCCACCGTGGCCATGGC AAGATCCATCTGCAGGTCCTCATGGAAGAGCCCCCTGAGCGGGACTCCACGGTGGCCGTG ATTGTGGGTGCCTCCGTCGGGGGCTTCCTGGCTGTGGTCATCTTGGTGCTGATGGTGGTC AAGTGTGTGAGGAGAAAAAAAGAGCAGAAGCTGAGCACAGATGACCTGAAGACCGAGGAG GAGGGCAAGACGGACGGTGAAGGCAACCCGGATGATGGCGCCAAGTAG

GenBank 基因 ID

AF007783

基因卡 ID

Genatlas ID

HGNC ID

HGNC:10589

染色体位置

11

轨迹

11q23

信号区域

2022/1/29 0:00:00

Pdb标识

KEGG ID

hsa:6327

细胞的位置

Membrane