同义词

XAP121

UniProt ID

O15247

UniProt名字

CLIC2_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

CLIC2

生物

Human

氨基酸序列

>lcl|BSEQ0009047|Chloride intracellular channel protein 2 MSGLRPGTQVDPEIELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEE LKDLAPGTNPPFLVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKESFDVGCNLFAKF SAYIKNTQKEANKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLT LADCSLLPKLNIIKVAAKKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENTYA NVAKQKS

目标基因序列

残基数

247

分子量

28356.1

理论 pI

一般功能

Voltage-gated ion channel activity

具体功能

Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx.

跨膜区

32-52

GenBank 蛋白质 ID

目标蛋白质序列

基因序列

>lcl|BSEQ0013583|Chloride intracellular channel protein 2 (CLIC2) ATGTCAGGCCTGCGGCCCGGCACTCAAGTGGACCCTGAGATTGAGCTTTTTGTAAAGGCT GGAAGTGATGGAGAGAGTATTGGAAACTGTCCCTTTTGCCAACGCCTTTTCATGATCCTC TGGCTTAAAGGAGTTAAATTTAATGTGACAACTGTTGACATGACCAGAAAGCCTGAAGAA CTAAAGGACTTAGCCCCAGGTACCAATCCTCCGTTCCTGGTGTATAACAAGGAGTTGAAA ACAGACTTCATTAAAATTGAGGAGTTTTTAGAACAAACCCTGGCTCCTCCAAGGTACCCT CACCTGAGTCCCAAGTACAAGGAGTCTTTTGATGTGGGCTGTAACCTCTTTGCCAAGTTT TCTGCATACATTAAGAATACACAAAAGGAGGCAAATAAGAATTTTGAAAAATCTCTGCTC AAAGAATTCAAGCGTCTGGATGACTACTTAAACACCCCACTTCTGGATGAAATTGATCCA GACAGTGCTGAGGAACCCCCAGTTTCCAGAAGACTATTCTTGGATGGGGACCAGCTAACA CTGGCTGATTGTAGCTTGTTACCCAAGCTGAACATTATTAAAGTTGCTGCCAAGAAATAT CGTGACTTTGACATTCCAGCAGAATTCTCAGGAGTCTGGCGTTATCTCCACAATGCCTAT GCCCGTGAAGAATTTACCCACACGTGTCCTGAAGACAAAGAAATTGAAAATACTTACGCA AATGTGGCTAAACAGAAGAGTTAG

GenBank 基因 ID

基因卡 ID

Genatlas ID

HGNC ID

HGNC:2063

染色体位置

轨迹

信号区域

Pdb标识

2PER; 2R4V; 2R5G

KEGG ID

hsa:1193

细胞的位置

Cytoplasm