同义词

Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex; E3-binding protein; E3BP; Lipoyl-containing pyruvate dehydrogenase complex component X; PDX1; proX

UniProt ID

O00330

UniProt名字

ODPX_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

PDHX

生物

Human

氨基酸序列

>lcl|BSEQ0008819|Pyruvate dehydrogenase protein X component, mitochondrial MAASWRLGCDPRLLRYLVGFPGRRSVGLVKGALGWSVSRGANWRWFHSTQWLRGDPIKIL MPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVEEGSK NIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTL RFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTAT PTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVPH AYATADCDLGAVLKVRQDLVKDDIKVSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPF IDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNL GMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDD ELATRFLKSFKANLENPIRLA

目标基因序列

残基数

501

分子量

54121.76

理论 pI

一般功能

Transferase activity, transferring acyl groups

具体功能

Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex.

跨膜区

GenBank 蛋白质 ID

目标蛋白质序列

基因序列

>lcl|BSEQ0020820|Pyruvate dehydrogenase protein X component, mitochondrial (PDHX) ATGCAATCAGGCGGCGCTGAGGGCAGCCCGGGGGCGGGGCGAACGGGGCGGGGGCCGGGG TCTGGTAAGGCCCCGCCGGCTGAGATATCCAGCGGCGCACCTGACTTCCCGGGAGGTGAT CCCATTAAGATACTAATGCCATCACTGTCTCCTACAATGGAAGAAGGAAACATTGTGAAA TGGCTGAAAAAGGAAGGTGAAGCGGTGAGTGCTGGAGATGCATTATGTGAAATTGAGACT GACAAAGCTGTGGTTACCTTAGATGCAAGTGATGATGGAATCTTGGCCAAAATCGTGGTT GAAGAAGGAAGTAAAAATATACGGCTAGGTTCACTAATTGGTTTGATAGTAGAAGAAGGA GAAGATTGGAAACATGTTGAAATTCCCAAAGACGTAGGTCCTCCACCACCAGTTTCAAAA CCTTCAGAGCCTCGCCCCTCACCAGAACCACAGATTTCCATCCCTGTCAAGAAGGAACAC ATACCCGGGACACTACGGTTCCGTTTAAGTCCAGCTGCCCGCAATATTCTGGAAAAACAC TCACTGGATGCTAGCCAGGGCACAGCCACTGGCCCTCGGGGGATATTCACTAAAGAGGAT GCTCTCAAACTTGTCCAGTTGAAACAAACGGGCAAGATTACCGAGTCCAGACCAACTCCA GCCCCCACAGCCACTCCCACAGCACCTTCGCCCCTACAGGCCACAGCTGGACCATCTTAT CCCCGGCCTGTGATCCCACCAGTATCAACTCCTGGACAACCCAATGCAGTGGGCACATTC ACTGAAATCCCCGCCAGCAATATTCGAAGAGTTATTGCCAAGAGATTAACTGAATCTAAA AGTACTGTACCTCATGCATATGCTACTGCTGACTGTGACCTTGGAGCTGTTTTAAAAGTT AGGCAAGATCTGGTCAAAGATGACATTAAAGTATCAGTAAATGATTTTATCATCAAGGCA GCAGCTGTTACCCTTAAACAAATGCCAGATGTTAATGTAAGCTGGGATGGAGAGGGCCCA AAGCAACTGCCATTTATTGACATTTCAGTGGCTGTGGCAACAGATAAAGGCTTACTTACT CCAATCATAAAAGATGCTGCTGCTAAAGGTATCCAGGAAATTGCTGACTCTGTAAAGGCT CTATCAAAGAAAGCAAGAGATGGAAAATTGTTGCCTGAAGAATACCAAGGAGGATCTTTT AGTATTTCCAACTTGGGGATGTTTGGCATCGACGAATTTACTGCAGTGATTAACCCTCCT CAGGCCTGCATTTTGGCGGTTGGGAGGTTCCGACCTGTGCTGAAGCTCACTGAGGATGAA GAGGGAAATGCCAAACTGCAGCAGCGCCAGCTCATAACAGTCACAATGTCAAGTGACAGT CGAGTGGTTGATGACGAACTGGCAACCAGGTTTCTTAAAAGTTTTAAAGCAAACCTAGAG AATCCTATCCGACTTGCCTAG

GenBank 基因 ID

基因卡 ID

Genatlas ID

HGNC ID

HGNC:21350

染色体位置

11

轨迹

信号区域

Pdb标识

1ZY8; 2DNC; 2F5Z; 2F60

KEGG ID

hsa:8050

细胞的位置

Mitochondrion matrix