同义词

Chloride channel ABP; G6; hRNCC; NCC27; Nuclear chloride ion channel 27; Regulatory nuclear chloride ion channel protein

UniProt ID

O00299

UniProt名字

CLIC1_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

CLIC1

生物

Human

氨基酸序列

>lcl|BSEQ0017672|Chloride intracellular channel protein 1 MAEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCP GGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKN SNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNL LPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKAL K

目标基因序列

残基数

241

分子量

26922.47

理论 pI

一般功能

Voltage-gated ion channel activity

具体功能

Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.

跨膜区

26-46

GenBank 蛋白质 ID

目标蛋白质序列

基因序列

>lcl|BSEQ0017673|Chloride intracellular channel protein 1 (CLIC1) ATGGCTGAAGAACAACCGCAGGTCGAATTGTTCGTGAAGGCTGGCAGTGATGGGGCCAAG ATTGGGAACTGCCCATTCTCCCAGAGACTGTTCATGGTACTGTGGCTCAAGGGAGTCACC TTCAATGTTACCACCGTTGACACCAAAAGGCGGACCGAGACAGTGCAGAAGCTGTGCCCA GGGGGGCAGCTCCCATTCCTGCTGTATGGCACTGAAGTGCACACAGACACCAACAAGATT GAGGAATTTCTGGAGGCAGTGCTGTGCCCTCCCAGGTACCCCAAGCTGGCAGCTCTGAAC CCTGAGTCCAACACAGCTGGGCTGGACATATTTGCCAAATTTTCTGCCTACATCAAGAAT TCAAACCCAGCACTCAATGACAATCTGGAGAAGGGACTCCTGAAAGCCCTGAAGGTTTTA GACAATTACTTAACATCCCCCCTCCCAGAAGAAGTGGATGAAACCAGTGCTGAAGATGAA GGTGTCTCTCAGAGGAAGTTTTTGGATGGCAACGAGCTCACCCTGGCTGACTGCAACCTG TTGCCAAAGTTACACATAGTACAGGTGGTGTGTAAGAAGTACCGGGGATTCACCATCCCC GAGGCCTTCCGGGGAGTGCATCGGTACTTGAGCAATGCCTACGCCCGGGAAGAATTCGCT TCCACCTGTCCAGATGATGAGGAGATCGAGCTCGCCTATGAGCAAGTGGCAAAGGCCCTC AAATAA

GenBank 基因 ID

基因卡 ID

Genatlas ID

HGNC ID

HGNC:2062

染色体位置

6

轨迹

信号区域

Pdb标识

1K0M; 1K0N; 1K0O; 1RK4; 3O3T; 3P8W; 3P90; 3QR6; 3SWL; 3TGZ; 3UVH; 4IQA; 4JZQ; 4K0G; 4K0N

KEGG ID

hsa:1192

细胞的位置

Nucleus