同义词

1.6.5.3; CI-23kD; Complex I-23kD; NADH-ubiquinone oxidoreductase 23 kDa subunit; TYKY subunit

UniProt ID

O00217

UniProt名字

NDUS8_HUMAN

目标UniProt ID

NCBI分类Id

9606

基因名称

NDUFS8

生物

Human

氨基酸序列

>lcl|BSEQ0009891|NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial MRCLTTPMLLRALAQAARAGPPGGRSLHSSAVAATYKYVNMQDPEMDMKSVTDRAARTLL WTELFRGLGMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAI CPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEE LLYNKEKLLNNGDKWEAEIAANIQADYLYR

目标基因序列

残基数

210

分子量

23704.795

理论 pI

6.27

一般功能

Nadh dehydrogenase (ubiquinone) activity

具体功能

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). May donate electrons to ubiquinone.

跨膜区

GenBank 蛋白质 ID

1935056

目标蛋白质序列

基因序列

>lcl|BSEQ0009892|NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (NDUFS8) ATGCGCTGCCTGACCACGCCTATGCTGCTGCGGGCCCTGGCCCAGGCTGCACGTGCAGGA CCTCCTGGTGGCCGGAGCCTCCACAGCAGTGCAGTGGCAGCCACCTACAAGTATGTGAAC ATGCAGGATCCCGAGATGGACATGAAGTCAGTGACTGACCGGGCAGCCCGCACCCTGCTG TGGACTGAGCTCTTCCGAGGCCTGGGCATGACCCTGAGCTACCTGTTCCGGGAACCGGCC ACCATCAACTACCCGTTCGAGAAGGGCCCGCTGAGCCCTCGCTTCCGTGGGGAGCATGCG CTGCGCCGGTACCCATCCGGGGAGGAGCGTTGCATTGCCTGCAAGCTCTGCGAGGCCATC TGCCCCGCCCAGGCCATCACCATCGAGGCTGAGCCAAGAGCTGATGGCAGCCGCCGGACC ACCCGCTATGACATCGACATGACCAAGTGCATCTACTGCGGCTTCTGCCAGGAGGCCTGT CCCGTGGATGCCATCGTCGAGGGCCCCAACTTTGAGTTCTCCACGGAGACCCATGAGGAG CTGCTGTACAACAAGGAGAAGTTGCTCAACAACGGGGACAAGTGGGAGGCCGAGATCGCC GCCAACATCCAGGCTGACTACTTGTATCGGTGA

GenBank 基因 ID

U65579

基因卡 ID

Genatlas ID

NDUFS8

HGNC ID

HGNC:7715

染色体位置

11

轨迹

11q13

信号区域

Pdb标识

KEGG ID

hsa:4728

细胞的位置

Mitochondrion