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Chloroform
目标名称
Potassium voltage-gated channel subfamily H member 6
作用机理
Chloroform has been shown to block HERG potassium channels, causing cardiac arrest. (A29)
参考文献
A29 - Scholz EP, Alter M, Zitron E, Kiesecker C, Kathofer S, Thomas D, Kreye VA, Kreuzer J, Becker R, Katus HA, Greten J, Karle CA: In vitro modulation of HERG channels by organochlorine solvent trichlormethane as potential explanation for proarrhythmic effects of chloroform. Toxicol Lett. 2006 Aug 20;165(2):156-66. Epub 2006 Mar 27. (16647228)
创建于
2009-04-22 22:04:17 UTC
更新于
2014-09-04 16:08:34 UTC