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O,P'-DDD
目标名称
Sodium/potassium-transporting ATPase subunit beta-2
作用机理
DDD inhibits neuronal adenosine triphosphatases (ATPases), particularly Na+K+-ATPase, and Ca2+-ATPase which play vital roles in neuronal repolarization. This reduces the rate of depolarization and increases the sensitivity of neurons to small stimuli that would not elicit a response in a fully depolarized neuron. (T10)
参考文献
T10 - Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
创建于
2009-04-14 21:08:40 UTC
更新于
2014-09-04 16:09:24 UTC