毒素T3DB ID

T3D0151

目标BioDB ID

BE0000132

目标名称

Androgen receptor

目标UniProt ID

P10275

作用机理

DDD is also believed to adversely affect the reproductive system by mimicking endogenous hormones and binding to the estrogen and adrogen receptors. (L85)

参考文献

A9667 - Maness SC, McDonnell DP, Gaido KW: Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells. Toxicol Appl Pharmacol. 1998 Jul;151(1):135-42. (9705896) L85 - ATSDR - Agency for Toxic Substances and Disease Registry (2005). Toxicological profile for DDT, DDE, and DDD. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA). (http://www.atsdr.cdc.gov/toxprofiles/tp35.html)

创建于

2009-04-14 21:08:40 UTC

更新于

2014-09-04 16:05:37 UTC

目标详情