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2,4-Dichlorophenol
作用机理
2,4-Dichlorophenol binds to androgen receptor. It inhibits 5a-dihydroxytestosterone's binding to androgen recpetor and also exhibits the synergistic androgenic activities.
参考文献
A3116 - Kim HJ, Park YI, Dong MS: Effects of 2,4-D and DCP on the DHT-induced androgenic action in human prostate cancer cells. Toxicol Sci. 2005 Nov;88(1):52-9. Epub 2005 Aug 17. (16107550)
A3117 - Li J, Ma M, Wang Z: In vitro profiling of endocrine disrupting effects of phenols. Toxicol In Vitro. 2010 Feb;24(1):201-7. doi: 10.1016/j.tiv.2009.09.008. Epub 2009 Sep 16. (19765641)
创建于
2013-04-23 17:22:34 UTC
更新于
2014-09-04 16:05:38 UTC