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Carbon monoxide
目标名称
Cytochrome c oxidase subunit 5A, mitochondrial
作用机理
Carbon monoxide can bind to cytochrome c oxidase, though with a lesser affinity than oxygen. This interferes with aerobic metabolism and efficient ATP synthesis. As a result, cells switch to anaerobic metabolism, causing anoxia, lactic acidosis, and eventual cell death. (L961)
参考文献
L961 - Wikipedia. Carbon monoxide poisoning. Last Updated 27 June 2009. (http://en.wikipedia.org/wiki/Carbon_monoxide_poisoning)
创建于
2009-06-29 19:19:40 UTC
更新于
2014-09-04 16:11:44 UTC