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P,P'-DDE
目标名称
Gamma-aminobutyric acid receptor subunit epsilon
作用机理
This organochloride antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of chloride ions and causing hyperexcitability of the central nervous system. (T10)
参考文献
T10 - Casarett LJ, Klaassen CD, and Watkins JB (2003). Casarett and Doull's essentials of toxicology. New York: McGraw-Hill/Medical Pub. Div.
创建于
2009-06-26 05:03:51 UTC
更新于
2014-09-04 16:15:00 UTC