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Lead-210
作用机理
Lead has been shown to competitively inhibit calcium's binding of calmodulin, interfering with neurotransmitter release. Lead binding of calmodulin causes improper activation, altering proper functioning of cAMP messenger pathways. (A20)
参考文献
A20 - Gill KD, Gupta V, Sandhir R: Ca2+/calmodulin-mediated neurotransmitter release and neurobehavioural deficits following lead exposure. Cell Biochem Funct. 2003 Dec;21(4):345-53. (14624473)
创建于
2009-06-25 16:13:45 UTC
更新于
2014-09-04 16:05:13 UTC